HuLPr27619

Uniprot ID

MYO19_HUMAN

Uniprot Acc

Q96H55;Q59GS4;Q9H5X2;

Protein name

Myosin-XIX

Comment

FUNCTION:Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. MYO19 is involved in mitochondrial motility.||SUBCELLULAR LOCATION:Cytoplasm, cytoskeleton. Mitochondrion outer membrane. Note=Probably associated with the outer membrane via its N-terminal mitochondrial targeting region.||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=4; Name=1; IsoId=Q96H55-1; Sequence=Displayed; Name=2; IsoId=Q96H55-2; Sequence=VSP 033402, VSP 033403; Name=3; IsoId=Q96H55-3; Sequence=VSP 033405, VSP 033406; Name=4; IsoId=Q96H55-4; Sequence=VSP 033404;||TISSUE SPECIFICITY:Widely expressed in multiple tissues and cell lines.||SIMILARITY:Contains 2 IQ domains.||SIMILARITY:Contains 1 myosin head-like domain.||SEQUENCE CAUTION:Sequence=BAD92272.1; Type=Erroneous initiation;

Subcellular localization

Cytoplasm, cytoskeleton.Mitochondrion outer membrane.

Gene name

myosin XIX

Protein sequence

MLQQVNGHNPGSDGQAREYLREDLQEFLGGEVLLYKLDDL TRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFK PVPQLYSPELMREYHAAPQPQKLKPHVFTVGEQTYRNVK SLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSPA SWESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRF GKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQASSERNF HIFYQICKGASEDERLQWHLPEGAAFSWLPNPERSLEED CFEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNIQFAA SEDEAQPCQPMDDAKYSVRTAASLLGLPEDVLLEMVQIR TIRAGRQQQVFRKPCARAECDTRRDCLAKLIYARLFDWL VSVINSSICADTDSWTTFIGLLDVYGFESFPDNSLEQLC INYANEKLQQHFVAHYLRAQQEEYAVEGLEWSFINYQDN QPCLDLIEGSPISICSLINEECRLNRPSSAAQLQTRIET ALAGSPCLGHNKLSREPSFIVVHYAGPVRYHTAGLVEKN KDPIPPELTRLLQQSQDPLLMGLFPTNPKEKTQEEPPGQ SRAPVLTVVSKFKASLEQLLQVLHSTTPHYIRCIKPNSQ GQAQTFLQEEVLSQLEACGLVETIHISAAGFPIRVSHRN FVERYKLLRRLHPCTSSGPDSPYPAKGLPEWCPHSEEAT LEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTK VFMTDSMLELLECGRARVLEQCARCIQGGWRRHRHREQE RQWRAVMLIQAAIRSWLTRKHIQRLHAAATVIKRAWQKW RIRMACLAAKELDGVEEKHFSQAPCSLSTSPLQTRLLEA IIRLWPLGLVLANTAMGVGSFQRKLVVWACLQLPRGSPS SYTVQTAQDQAGVTSIRALPQGSIKFHCRKSPLRYADIC PEPSPYSITGFNQILLERHRLIHVTSSAFTGLG

Database cross reference

RefSeq Protein accession:NP_001028752
RefSeq Protein gi:75812980

HLPP validation

Yes/No

Yes

Project name

French Liver;Chinese Liver;Human Liver Organelles;

GO:0005741;C:mitochondrial outer membrane;IEA:UniProtKB-SubCell. GO:0016459;C:myosin complex;IEA:UniProtKB-KW.

GO-F

GO:0003779;F:actin binding;IEA:UniProtKB-KW. GO:0005524;F:ATP binding;IEA:UniProtKB-KW. GO:0003774;F:motor activity;IEA:UniProtKB-KW.

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr27619

PHOSPHORYLATION

353

T

PhosphoSitePlus

18012637

LTP

N