Protein basic information
| LiverAtlas Protein ID |
HuLPr27687 |
|
Uniprot ID |
|
|
Uniprot Acc |
Q147X3;Q0IIN2; |
|
Protein name |
N-alpha-acetyltransferase 30, NatC catalytic subunit |
|
Comment |
FUNCTION:Catalytic subunit of the N-terminal acetyltransferase C (NatC) complex. Catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Leu-Ala and Met-Leu-Gly. Necessary for the lysosomal localization and function of ARL8B.||CATALYTIC ACTIVITY:Acetyl-CoA + peptide = N(alpha)-acetylpeptide + CoA.||SUBUNIT:Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, LSMD1 and NAA30.||SUBCELLULAR LOCATION:Cytoplasm.||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q147X3-1; Sequence=Displayed; Name=2; IsoId=Q147X3-2; Sequence=VSP 031581; Note=No experimental confirmation available;||SIMILARITY:Belongs to the acetyltransferase family. MAK3 subfamily.||SIMILARITY:Contains 1 N-acetyltransferase domain. |
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Subcellular localization |
Cytoplasm. |
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Gene name |
|
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Protein sequence
|
MAEVPPGPSSLLPPPAPPAPAAVEPRCPFPAGAALACCSE DEEDDEEHEGGGSRSPAGGESATVAAKGHPCLRCPQPPQ EQQQLNGLISPELRHLRAAASLKSKVLSVAEVAATTATP DGGPRATATKGAGVHSGERPPHSLSSNARTAVPSPVEAA AASDPAAARNGLAEGTEQEEEEEDEQVRLLSSSLTADCS LRSPSGREVEPGEDRTIRYVRYESELQMPDIMRLITKDL SEPYSIYTYRYFIHNWPQLCFLAMVGEECVGAIVCKLDM HKKMFRRGYIAMLAVDSKYRRNGIGTNLVKKAIYAMVEG DCDEVVLETEITNKSALKLYENLGFVRDKRLFRYYLNGV DALRLKLWLR |
|
Database cross reference |
RefSeq Protein accession:NP_001011713
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Liver relevance
|
HLPP validation |
Yes/No |
Yes |
|
Project name |
Chinese Liver; |
Ontology annotation
| GO-C |
GO:0005737;C:cytoplasm;IEA:UniProtKB-SubCell. |
|
GO-F |
GO:0004596;F:peptide alpha-N-acetyltransferase activity;IEA:EC. |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
|
HuLPr27687 |
PHOSPHORYLATION |
134 |
S |
PhosphoSitePlus |
LTP |
N |
 
|
|
|
HuLPr27687 |
PHOSPHORYLATION |
117 |
T |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr27687 |
ACETYLATION |
233 |
K |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr27687 |
PHOSPHORYLATION |
152 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr27687 |
PHOSPHORYLATION |
190 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr27687 |
PHOSPHORYLATION |
196 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr27687 |
PHOSPHORYLATION |
199 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr27687 |
PHOSPHORYLATION |
39 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr27687 |
PHOSPHORYLATION |
55 |
S |
PhosphoSitePlus |
LTP |
N |
|
