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Protein basic information

LiverAtlas Protein ID

HuLPr27735

Uniprot ID

NANG2_HUMAN

Uniprot Acc

Q8N7R0;

Protein name

Putative homeobox protein NANOG2

Comment

FUNCTION:Probable transcriptional regulator.||SUBCELLULAR LOCATION:Nucleus (By similarity).||DEVELOPMENTAL STAGE:Expressed in embryonic stem cells (ES).||SIMILARITY:Belongs to the Nanog homeobox family.||SIMILARITY:Contains 1 homeobox DNA-binding domain.||CAUTION:Could be the product of a pseudogene. According to PubMed:15233988.||CAUTION:Exists an other tandem duplicated gene (NANOG) and 10 other NANOG-related nucleotide sequences located on different chromosomes, all of which are processed pseudogenes lacking introns (NANOGP2 to NANOGP11); except NANOGP8 which is a retrogene.

Subcellular localization

Nucleus(By similarity).

Gene name

Nanog homeobox pseudogene 8

Protein sequence

MDLPIQDSHDSSTSPKGKQPTTAEKSATKKEDKVPVKKQK TRTVFSSTQLCVLNDRFQRQKYLSLQQMQELSNILNLSY KQVKTWFQNQRMKSKRWQKNNWLKNSNGVTQGCLVNPTG NLPMWSNQTWNNSTWSNQTQNIQSWSNHSWNTQTWCTQS WNNQAWNSPFYNCGEESLQSCMQFQPNSPASDLQAALEA AGEGLNVIQQTTRYFNTPQTMDLFLNYSMNMQPEDV

Database cross reference


Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

Ontology annotation

GO-C

GO:0005634;C:nucleus;IEA:UniProtKB-SubCell.

GO-F

GO:0043565;F:sequence-specific DNA binding;IEA:InterPro. GO:0003700;F:sequence-specific DNA binding transcription factor activity;IEA:InterPro.