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Protein basic information

LiverAtlas Protein ID

HuLPr27794

Uniprot ID

NCF1B_HUMAN

Uniprot Acc

A6NI72;

Protein name

Putative neutrophil cytosol factor 1B

Comment

FUNCTION:May be required for activation of the latent NADPH oxidase (necessary for superoxide production) (By similarity).||SUBCELLULAR LOCATION:Cytoplasm (By similarity).||SIMILARITY:Contains 1 PX (phox homology) domain.||SIMILARITY:Contains 2 SH3 domains.||CAUTION:Could be the product of a pseudogene.

Subcellular localization

Cytoplasm(By similarity).

Gene name

neutrophil cytosolic factor 1B pseudogene

Protein sequence

MGDTFIRHIALLGFEKRFVPSQHYVRYMFLVKWQDLSEKV VYRRFTEIYEFHKTLKEMFPIEAGAINPENRIIPHLPAP KWFDGQRAAENHQGTLTEYCGTLMSLPTKISRCPHLLDF FKVRPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPI ILQTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWF CQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAI KAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTG YFPSMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNVHSIH QRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLE EERQTQRSKPQPAVPPRPSADLILNRCSESTKRKLASAV

Database cross reference


Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;

Ontology annotation

GO-C

GO:0005737;C:cytoplasm;IEA:UniProtKB-SubCell.

GO-F

GO:0035091;F:phosphatidylinositol binding;IEA:InterPro. GO:0016175;F:superoxide-generating NADPH oxidase activity;IEA:InterPro.

GO-P

GO:0007154;P:cell communication;IEA:InterPro.