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Protein basic information

LiverAtlas Protein ID

HuLPr27945

Uniprot ID

NEU1B_HUMAN

Uniprot Acc

A8MQ27;

Protein name

E3 ubiquitin-protein ligase NEURL1B

Comment

FUNCTION:E3 ubiquitin-protein ligase (By similarity).||PATHWAY:Protein modification; protein ubiquitination.||SIMILARITY:Contains 2 NHR (neuralized homology repeat) domains.||SIMILARITY:Contains 1 RING-type zinc finger.

Gene name

neuralized homolog 1B (Drosophila)

Protein sequence

MGNTVHRTLPDPSPPARLLATRPCCGPGPERRPVLGEAPR FHAQAKGKNVRLDGHSRRATRRNSFCNGVTFTQRPIRLY EQVRLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYA CPDLVTRPGYWAKALPENLALRDTVLAYWADRHGRVFYS VNDGEPVLFHCGVAVGGPLWALIDVYGITDEVQLLESAF ADTLTPARLSQARFSACLPPSSHDAANFDNNELENNQVV AKLGHLALGRAPGPPPADAAAAAIPCGPRERPRPASSPA LLEADLRFHATRGPDVSLSADRKVACAPRPDGGRTLVFS ERPLRPGESLFVEVGRPGLAAPGALAFGITSCDPGVLRP NELPADPDALLDRKEYWVVARAGPVPSGGDALSFTLRPG GDVLLGINGRPRGRLLCVDTTQALWAFFAVRGGVAGQLR LLGTLQSSPATTTPSGSLSGSQDDSDSDMTFSVNQSSSA SESSLVTAPSSPLSPPVSPVFSPPEPAGIKNGECTVCFD GEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKIYRP

Database cross reference

RefSeq Protein accession:NP_001136123
RefSeq Protein gi:217416388

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

Ontology annotation

GO-F

GO:0016874;F:ligase activity;IEA:UniProtKB-KW. GO:0008270;F:zinc ion binding;IEA:InterPro.