HuLPr28476

Uniprot ID

O11H7_HUMAN

Uniprot Acc

Q8NGC8;

Protein name

Olfactory receptor 11H7

Comment

FUNCTION:Odorant receptor. Activated by isovaleric acid.||SUBCELLULAR LOCATION:Cell membrane; Multi-pass membrane protein.||POLYMORPHISM:A stop codon in the gene coding for this protein at position Gln-227 is responsible for functional diversity thus producing a pseudogene. Hypersensitivity towards isovaleric acid is seen predominantly in individuals who carry at least one copy of the intact allele.||SIMILARITY:Belongs to the G-protein coupled receptor 1 family.||WEB RESOURCE:Name=Human Olfactory Receptor Data Exploratorium (HORDE); URL="http://bip.weizmann.ac.il/cgi-bin/HORDE/showGene.pl?key=symbol&value=OR11H7P";

Subcellular localization

Cell membrane;Multi-pass membrane protein.

Gene name

olfactory receptor, family 11, subfamily H, member 7 (gene/pseudogene)

Protein sequence

MNNSQISTVTQFVLLGFPGPWKIQIIFFSMILLVYIFTLT GNMAIICAVRWDHRLHTPMYVLLANFSFLEIWYVTCTVP NMLVNFFSKTKTISFSGCFTQFHFFFSLGTTECFFLCVM AYDRYLAICHPLHYPSIMTGQLCGILVSLCWLIGFLGHS ISIFFIFQLPFCGPNIIDHFLCDVDPLMALSSAPTHIIG HVFHSVSSLFINLTMVYILGSYTLVLRTVLQVPSSAGWQ KAISTCGSHLVVVSLFYGAIMLMYVSPTPGNSVAMHKLI TLIYSVVTPVLNPLIYSLRNKDMKYALHHVFCGMRIIQRS

Database cross reference

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

GO:0016021;C:integral to membrane;IEA:UniProtKB-KW. GO:0005886;C:plasma membrane;IEA:UniProtKB-SubCell.

GO-F

GO:0004984;F:olfactory receptor activity;IEA:InterPro.