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Gene, Transcriptome, Protein, Pathway or Disease. 

Protein basic information

LiverAtlas Protein ID

HuLPr29432

Uniprot ID

PCDGK_HUMAN

Uniprot Acc

Q9UN70;O60622;Q08192;Q9Y5C4;

Protein name

Protocadherin gamma-C3

Comment

FUNCTION:Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.||SUBCELLULAR LOCATION:Cell membrane; Single-pass type I membrane protein (By similarity).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=4; Name=1; IsoId=Q9UN70-1; Sequence=Displayed; Name=2; Synonyms=Short; IsoId=Q9UN70-2; Sequence=VSP 008698, VSP 008699; Name=3; Synonyms=PC43-11; IsoId=Q9UN70-3; Sequence=VSP 009675, VSP 009676; Name=4; Synonyms=PC43-12; IsoId=Q9UN70-4; Sequence=VSP 009673, VSP 009674;||SIMILARITY:Contains 6 cadherin domains.||SEQUENCE CAUTION:Sequence=AAA75391.1; Type=Frameshift; Positions=905;

Subcellular localization

Cell membrane;Single-pass type I membrane protein(By similarity).

Gene name

protocadherin gamma subfamily C, 3

Protein sequence

MVPEAWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEE REKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEV NRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLEL FSVEVVIQDINDNNPAFPTQEMKLEISEAVAPGTRFPLE SAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAEL VLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVL DANDNAPVFNQSLYRARVLEDAPSGTRVVQVLATDLDEG PNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFE DTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEI TVTSVYSPVPEDAPLGTVIALLSVTDLDAGENGLVTCEV PPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITAR DAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEEN NLPGAPILNLSVWDPDAPQNARLSFFLLEQGAETGLVGR YFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVL ATNISVNIFVTDRNDNAPQVLYPRPGGSSVEMLPRGTSA GHLVSRVVGWDADAGHNAWLSYSLLGSPNQSLFAIGLHT GQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTV SVTEDSPEARAEFPSGSAPREQKKNLTFYLLLSLILVSV GFVVTVFGVIIFKVYKWKQSRDLYRAPVSSLYRTPGPSL HADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASP LASRQNTLRSCDPVFYRQVLGAESAPPGQQAPPNTDWRF SQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASAS EAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVY IPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK

Database cross reference

RefSeq Protein accession:NP_002579
RefSeq Protein gi:14277675

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0016021;C:integral to membrane;IEA:UniProtKB-KW. GO:0005886;C:plasma membrane;IEA:UniProtKB-SubCell.

GO-F

GO:0005509;F:calcium ion binding;IEA:InterPro.

GO-P

GO:0016339;P:calcium-dependent cell-cell adhesion;NAS:UniProtKB. GO:0007156;P:homophilic cell adhesion;IEA:InterPro.

Post-translational modification

LiverAtlas Protein ID

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr29432

PHOSPHORYLATION

60

S

Phospho-ELM

42598

HTP

N

HuLPr29432

PHOSPHORYLATION

575

S

PhosphoSitePlus

10940362

LTP

N

HuLPr29432

PHOSPHORYLATION

60

S

PhosphoSitePlus

3215985

LTP

N

Pathway

Pathway name

TGF_beta_Receptor