Protein basic information
| LiverAtlas Protein ID |
HuLPr29658 |
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Uniprot ID |
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Uniprot Acc |
Q6PCE3;Q96MQ7;Q9UIK3; |
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Protein name |
Glucose 1,6-bisphosphate synthase |
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Comment |
FUNCTION:Glucose 1,6-bisphosphate synthase using 1,3- bisphosphoglycerate as a phosphate donor and a series of 1- phosphate sugars as acceptors, including glucose 1-phosphate, mannose 1-phosphate, ribose 1-phosphate and deoxyribose 1- phosphate. 5 or 6-phosphosugars are bad substrates, with the exception of glucose 6-phosphate. Also synthesizes ribose 1,5- bisphosphate. Has only low phosphopentomutase and phosphoglucomutase activities.||CATALYTIC ACTIVITY:3-phospho-D-glyceroyl phosphate + alpha-D- glucose 1-phosphate = 3-phospho-D-glycerate + alpha-D-glucose 1,6- bisphosphate.||SIMILARITY:Belongs to the phosphohexose mutase family. |
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Gene name |
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Protein sequence
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MAENTEGDLNSNLLHAPYHTGDPQLDTAIGQWLRWDKNPK TKEQIENLLRNGMNKELRDRLCCRMTFGTAGLRSAMGAG FCYINDLTVIQSTQGMYKYLERCFSDFKQRGFVVGYDTR GQVTSSCSSQRLAKLTAAVLLAKDVPVYLFSRYVPTPFV PYAVQKLKAVAGVMITASHNRKEDNGYKVYWETGAQITS PHDKEILKCIEECVEPWNGSWNDNLVDTSPLKRDPLQDI CRRYMEDLKKICFYRELNSKTTLKFVHTSFHGVGHDYVQ LAFKVFGFKPPIPVPEQKDPDPDFSTVKCPNPEEGESVL ELSLRLAEKENARVVLATDPDADRLAAAELQENGCWKVF TGNELAALFGWWMFDCWKKNKSRNADVKNVYMLATTVSS KILKAIALKEGFHFEETLPGFKWIGSRIIDLLENGKEVL FAFEESIGFLCGTSVLDKDGVSAAVVVAEMASYLETMNI TLKQQLVKVYEKYGYHISKTSYFLCYEPPTIKSIFERLR NFDSPKEYPKFCGTFAILHVRDVTTGYDSSQPNKKSVLP VSKNSQMITFTFQNGCVATLRTSGTEPKIKYYAEMCASP DQSDTALLEEELKKLIDALIENFLQPSKNGLIWRSV |
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Database cross reference |
RefSeq Protein accession:NP_775853
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Liver relevance
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HLPP validation |
Yes/No |
Yes |
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Project name |
Chinese Liver;Human Liver Organelles; |
Ontology annotation
| GO-C |
GO:0005829;C:cytosol;ISS:RefGenome. |
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GO-F |
GO:0047933;F:glucose-1,6-bisphosphate synthase activity;IEA:EC. GO:0004614;F:phosphoglucomutase activity;ISS:RefGenome. |
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GO-P |
GO:0019255;P:glucose 1-phosphate metabolic process;ISS:RefGenome. |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
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HuLPr29658 |
PHOSPHORYLATION |
175 |
S |
Phospho-ELM |
HTP |
yes |
 
|
|
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HuLPr29658 |
PHOSPHORYLATION |
159 |
Y |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr29658 |
PHOSPHORYLATION |
175 |
S |
PhosphoSitePlus |
LTP |
yes |
|
|
|
HuLPr29658 |
PHOSPHORYLATION |
173 |
T |
PhosphoSitePlus |
LTP |
N |
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Pathway
| Pathway name |
