HuLPr30310

Uniprot ID

PRR5L_HUMAN

Uniprot Acc

Q6MZQ0;A4QN22;Q96H46;Q9H7V4;

Protein name

Proline-rich protein 5-like

Comment

FUNCTION:May be part of the TORC2 complex which plays a critical role in AKT1 'Ser-473' phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization.||SUBUNIT:May replace PRR5 in the target of rapamycin 2 complex (TORC2) comprised of MTOR, LST8, PRR5, RICTOR and MAPKAP1.||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q6MZQ0-1; Sequence=Displayed; Name=2; IsoId=Q6MZQ0-2; Sequence=VSP 033375, VSP 033379; Note=No experimental confirmation available; Name=3; IsoId=Q6MZQ0-3; Sequence=VSP 033376, VSP 033377, VSP 033378; Note=No experimental confirmation available;||SIMILARITY:Belongs to the PROTOR family.||SEQUENCE CAUTION:Sequence=AAI25123.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;

Gene name

proline rich 5 like

Protein sequence

MTRGFAPILPVEFHKMGSFRRPRPRFMSSPVLSDLPRFQA ARQALQLSSSSAWNSVQTAVINVFKGGGLQSNELYALNE NIRRLLKSELGSFITDYFQNQLLAKGLFFVEEKIKLCEG ENRIEVLAEVWDHFFTETLPTLQAIFYPVQGQELTIRQI SLLGFRDLVLLKVKLGDLLLLAQSKLPSSIVQMLLILQS VHEPTGPSESYLQLEELVKQVVSPFLGISGDRSFSGPTY TLARRHSRVRPKVTVLNYASPITAVSRPLNEMVLTPLTE QEGEAYLEKCGSVRRHTVANAHSDIQLLAMATMMHSGLG EEASSENKCLLLPPSFPPPHRQCSSEPNITDNPDGLEEG ARGSQEGSELNCASLS

Database cross reference

RefSeq Protein accession:NP_001153639
RefSeq Protein gi:237757351

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr30310

PHOSPHORYLATION

28

S

PhosphoSitePlus

4789021

HTP

N