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Protein basic information

LiverAtlas Protein ID

HuLPr30502

Uniprot ID

PTSS2_HUMAN

Uniprot Acc

Q9BVG9;

Protein name

Phosphatidylserine synthase 2

Comment

FUNCTION:Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine is replaced by L-serine.||ENZYME REGULATION:Inhibited by excess phosphatidylserine, but not by phosphatidylcholine or phosphatidylethanolamine (By similarity).||PATHWAY:Phospholipid metabolism; phosphatidylserine biosynthesis.||SUBCELLULAR LOCATION:Membrane; Multi-pass membrane protein.||SIMILARITY:Belongs to the phosphatidyl serine synthase family.

Subcellular localization

Membrane;Multi-pass membrane protein.

Gene name

phosphatidylserine synthase 2

Protein sequence

MRRGERRDAGGPRPESPVPAGRASLEEPPDGPSAGQATGP GEGRRSTESEVYDDGTNTFFWRAHTLTVLFILTCTLGYV TLLEETPQDTAYNTKRGIVASILVFLCFGVTQAKDGPFS RPHPAYWRFWLCVSVVYELFLIFILFQTVQDGRQFLKYV DPKLGVPLPERDYGGNCLIYDPDNETDPFHNIWDKLDGF VPAHFLGWYLKTLMIRDWWMCMIISVMFEFLEYSLEHQL PNFSECWWDHWIMDVLVCNGLGIYCGMKTLEWLSLKTYK WQGLWNIPTYKGKMKRIAFQFTPYSWVRFEWKPASSLRR WLAVCGIILVFLLAELNTFYLKFVLWMPPEHYLVLLRLV FFVNVGGVAMREIYDFMDDPKPHKKLGPQAWLVAAITAT ELLIVVKYDPHTLTLSLPFYISQCWTLGSVLALTWTVWR FFLRDITLRYKETRWQKWQNKDDQGSTVGNGDQHPLGLD EDLLGPGVAEGEGAPTPN

Database cross reference

RefSeq Protein accession:NP_110410
RefSeq Protein gi:13540555

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

Ontology annotation

GO-C

GO:0016021;C:integral to membrane;IEA:UniProtKB-KW.

Post-translational modification

LiverAtlas Protein ID

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr30502

PHOSPHORYLATION

16

S

Phospho-ELM

12918

HTP

N

HuLPr30502

PHOSPHORYLATION

485

T

PhosphoSitePlus

4270231

HTP

N

HuLPr30502

PHOSPHORYLATION

16

S

PhosphoSitePlus

471220

LTP

N

Pathway

Pathway name

Phospholipid_Biosynthesis