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Protein basic information

LiverAtlas Protein ID

HuLPr31232

Uniprot ID

Q14BD3_HUMAN

Uniprot Acc

Q14BD3;

Protein name

Intersectin 1 (SH3 domain protein)

Comment

SIMILARITY:Contains 1 C2 domain.||SIMILARITY:Contains 1 DH (DBL-homology) domain.||SIMILARITY:Contains 1 PH domain.||SIMILARITY:Contains 5 SH3 domains.

Gene name

intersectin 1 (SH3 domain protein)

Protein sequence

MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFIT GDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFS IAMKLIKLKLQGYQLPSALPPVMKQQPVAISSAPAFGMG GIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPP LANGAPPVIQPLPAFAHPAATLPKSSSFSRSGPGSQLNT KLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKT MSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKL TAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRS GSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFED KKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQ ERKERERQEQERKRQLELEKQLEKQRELERQREEERRKE IERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIV VLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQ EIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQI LNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQL DEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSM EAERLKQKEQERKIIELEKQKEEAQRRAQERDKQWLEHV QQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQD KLGRLFHQHQEPAKPAVQAPWSTAEKGPLTISAQENVKV VYYRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGE PGWLGGELKGKTGWFPANYAEKIPENEVPAPVKPVTDST SAPAPKLALRETPAPLAVTSSEPSTTPNNWADFSSTWPT STNEKPETDNWDAWAAQPSLTVPSAGQLRQRSAFTPATA TGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKN DVITVLEQQDMWWFGEVQGQKGWFPKSYVKLISGPIRKS TSMDSGSSESPASLKRVASPAAKP

Database cross reference

RefSeq Protein accession:NP_001001132
RefSeq Protein gi:47717125

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0005622;C:intracellular;IEA:InterPro. GO:0005886;C:plasma membrane;IDA:HPA.

GO-F

GO:0005509;F:calcium ion binding;IEA:InterPro. GO:0005089;F:Rho guanyl-nucleotide exchange factor activity;IEA:InterPro.

GO-P

GO:0035556;P:intracellular signal transduction;IEA:InterPro. GO:0035023;P:regulation of Rho protein signal transduction;IEA:InterPro.

Pathway

Pathway name

TCR