HuLPr31236

Uniprot ID

Q14C66_HUMAN

Uniprot Acc

Q14C66;

Protein name

ADAM8 protein

Comment

SIMILARITY:Contains 1 disintegrin domain.||SIMILARITY:Contains 1 peptidase M12B domain.

Gene name

ADAM metallopeptidase domain 8

Protein sequence

MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPRRLPGP RVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLL GSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSA ASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQA EHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPS RETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDK LYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTW QARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHS SGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCR CQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERP QSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDC RNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPK KDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGAC PTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRAD MCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVP EGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNH KQECHCHAGWAPPHCAKLLTEVHAASGSLPVLVVVVLVL LAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLF HQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASS VALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAP PVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP

Database cross reference

RefSeq Protein accession:NP_001100
RefSeq Protein gi:256773264

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

GO-F

GO:0004222;F:metalloendopeptidase activity;IEA:InterPro. GO:0008270;F:zinc ion binding;IEA:InterPro.

GO-P

GO:0007229;P:integrin-mediated signaling pathway;IEA:UniProtKB-KW. GO:0006508;P:proteolysis;IEA:InterPro.

IL2