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Gene, Transcriptome, Protein, Pathway or Disease. 

Protein basic information

LiverAtlas Protein ID

HuLPr31585

Uniprot ID

Q1RPB8_HUMAN

Uniprot Acc

Q1RPB8;

Protein name

MHC class I antigen

Comment

FUNCTION:Involved in the presentation of foreign antigens to the immune system (By similarity).||SIMILARITY:Belongs to the MHC class I family.||SIMILARITY:Contains 1 Ig-like C1-type (immunoglobulin-like) domain.

Gene name

major histocompatibility complex, class I, B

Protein sequence

MRVTAPRTLLLLLWGAVALTETWAGSHSMRYFYTAMSRPG RGEPRFITVGYVDDTLFVRFDSDATSPRKEPRAPWIEQE GPEYWDRETQISKTNTQTYRESLRNLRGYYNQSEAGSHI IQRMYGCDVGPDGRLLRGYDQDAYDGKDYIALNEDLSSW TAADTAAQITQRKWEAARVAEQLRAYLEGLCVESLRRYL ENGKETLQRADPPKTHVTHHPISDHEVTLRCWALGFYPA EITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP SGEEQRYTCHVQHEGLPKPLTLRWEPSSQSTVPIVGIVA GLAVLAVVVIGAVVAAVMCRRKSSGGKGGSYSQAACSDS AQGSDVSLTA

Database cross reference

RefSeq Protein accession:NP_005505
RefSeq Protein gi:17986001

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;

Ontology annotation

GO-C

GO:0016021;C:integral to membrane;IEA:UniProtKB-KW. GO:0042612;C:MHC class I protein complex;IEA:UniProtKB-KW.

GO-P

GO:0002474;P:antigen processing and presentation of peptide antigen via MHC class I;IEA:UniProtKB-KW. GO:0006955;P:immune response;IEA:InterPro.

Pathway

Pathway name

TCR

Pathway name

IL1

Pathway name

RANKL