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Protein basic information

LiverAtlas Protein ID

HuLPr31993

Uniprot ID

Q2VF42_HUMAN

Uniprot Acc

Q2VF42;

Protein name

Glucose-6-phosphate 1-dehydrogenase

Comment

CATALYTIC ACTIVITY:D-glucose 6-phosphate + NADP(+) = D-glucono- 1,5-lactone 6-phosphate + NADPH.||PATHWAY:Carbohydrate degradation; pentose phosphate pathway.||SIMILARITY:Belongs to the glucose-6-phosphate dehydrogenase family.

Gene name

glucose-6-phosphate dehydrogenase

Protein sequence

GDLAKKKIYPTIWWLFRDGLLPENTFIVGYARSRLTVADI RKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQ RLNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESC MSQIGWNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIY RIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILT FKEPFGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEK PASTNSDDVRDEKVKVLKCISEVQANNVVLGQYVGNPDG EGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVP FILRCGKALNERKAEVRLQFHDVAGDIFHQQCKRNELVI RVQPNEAVYTKMMTKKPGMFFNPEESELDLTYGNRYKNV KLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLH QIELEKPKPIPYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL

Database cross reference

RefSeq Protein accession:NP_000393
RefSeq Protein gi:109389365

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-F

GO:0004345;F:glucose-6-phosphate dehydrogenase activity;IEA:EC. GO:0050661;F:NADP binding;IEA:InterPro.

GO-P

GO:0006006;P:glucose metabolic process;IEA:UniProtKB-KW.

Pathway

Pathway name

TGF_beta_Receptor