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Gene, Transcriptome, Protein, Pathway or Disease. 

Protein basic information

LiverAtlas Protein ID

HuLPr32484

Uniprot ID

Q498Y2_HUMAN

Uniprot Acc

Q498Y2;

Protein name

USP3 protein

Comment

CATALYTIC ACTIVITY:Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C- terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).||SIMILARITY:Contains 1 UBP-type zinc finger.

Gene name

ubiquitin specific peptidase 3

Protein sequence

MECPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWV CLTCSSVHCGRYVNGHAKKHYEDAQVPLTNHKKSEKQDK VQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHL QNLENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAIC ATGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELR NGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQT AFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHL ELQGGFNGVSRSAILQENSTLSASNKCCINGASTVVTAI FGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKR SKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKKK

Database cross reference

RefSeq Protein accession:NP_006528
RefSeq Protein gi:55770886

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;

Ontology annotation

GO-F

GO:0008234;F:cysteine-type peptidase activity;IEA:UniProtKB-KW. GO:0004221;F:ubiquitin thiolesterase activity;IEA:InterPro. GO:0008270;F:zinc ion binding;IEA:InterPro.

GO-P

GO:0006511;P:ubiquitin-dependent protein catabolic process;IEA:InterPro.