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Protein basic information

LiverAtlas Protein ID

HuLPr33847

Uniprot ID

Q53SF8_HUMAN

Uniprot Acc

Q53SF8;

Protein name

Putative uncharacterized protein SOS1

Comment

SIMILARITY:Contains 1 DH (DBL-homology) domain.||SIMILARITY:Contains 1 N-terminal Ras-GEF domain.||SIMILARITY:Contains 1 PH domain.||SIMILARITY:Contains 1 Ras-GEF domain.

Gene name

son of sevenless homolog 1 (Drosophila)

Protein sequence

VQGQVHPTLESNDDALQYVEELILQLLNMLCQAQPRSASD VEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVE KIHPLLKEVLGYKIDHQVSVYIVAVLEYISADILKLVGN YVRNIRHYEITKQDIKVAMCADKVLMDMFHQDVEDINIL SLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKV FREPFVSNSKLFSANDVENIFSRIVDIHELSVKLLGHIE DTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYARDIL RPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRL LLAPVYHCLHYFELLKQLEEKSEDQEDKECLKQAITALL NVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHER HIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRK VQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNW MAALISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYR FAEPDSEENIIFEENMQPKAGIPIIKAGTVIKLIERLTY HMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPE PTEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVC RHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVES ITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHI ETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWT KEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERV AVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDH TFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCV PFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAE ITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEF TDYLFNKSLEIEPRNPKPLPRFPK

Database cross reference

RefSeq Protein accession:NP_005624
RefSeq Protein gi:15529996

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;French Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0005622;C:intracellular;IEA:InterPro.

GO-F

GO:0003677;F:DNA binding;IEA:InterPro. GO:0005089;F:Rho guanyl-nucleotide exchange factor activity;IEA:InterPro.

GO-P

GO:0035023;P:regulation of Rho protein signal transduction;IEA:InterPro.

Pathway

Pathway name

IL2

Pathway name

IL4