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Protein basic information

LiverAtlas Protein ID

HuLPr33850

Uniprot ID

Q53SH4_HUMAN

Uniprot Acc

Q53SH4;

Protein name

Cholinergic receptor, nicotinic, alpha 1 (Muscle), isoform CRA a

Comment

SUBCELLULAR LOCATION:Membrane; Multi-pass membrane protein (By similarity).||SIMILARITY:Belongs to the ligand-gated ion channel (TC 1.A.9) family.

Subcellular localization

Membrane;Multi-pass membrane protein(By similarity).

Gene name

cholinergic receptor, nicotinic, alpha 1 (muscle)

Protein sequence

MEPWPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVR PVEDHRQVVEVTVGLQLIQLINVDEVNQIVTTNVRLKQQ WVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNADG DFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPF DEQNCSMKLGTWTYDGSVVAINPESDQPDLSNFMESGEW VIKESRGWKHSVTYSCCPDTPYLDITYHFVMQRLPLYFI VNVIIPCLLFSFLTGLVFYLPTDSGEKMTLSISVLLSLT VFLLVIVELIPSTSSAVPLIGKYMLFTMVFVIASIIITV IVINTHHRSPSTHVMPNWVRKVFIDTIPNIMFFSTMKRP SREKQDKKIFTEDIDISDISGKPGPPPMGFHSPLIKHPE VKSAIEGIKYIAETMKSDQESNNAAAEWKYVAMVMDHIL LGVFMLVCIIGTLAVFAGRLIELNQQG

Database cross reference

RefSeq Protein accession:NP_000070
RefSeq Protein gi:4557457

Ontology annotation

GO-C

GO:0030054;C:cell junction;IEA:UniProtKB-KW. GO:0016021;C:integral to membrane;IEA:UniProtKB-KW. GO:0045211;C:postsynaptic membrane;IEA:UniProtKB-KW.

GO-F

GO:0004889;F:nicotinic acetylcholine-activated cation-selective channel activity;IEA:InterPro. GO:0004872;F:receptor activity;IEA:UniProtKB-KW.