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Protein basic information

LiverAtlas Protein ID

HuLPr34195

Uniprot ID

Q58F15_HUMAN

Uniprot Acc

Q58F15;

Protein name

Ephrin receptor

Comment

CATALYTIC ACTIVITY:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.||SUBCELLULAR LOCATION:Membrane; Single-pass type I membrane protein (By similarity).||SIMILARITY:Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.||SIMILARITY:Contains 1 SAM (sterile alpha motif) domain.||SIMILARITY:Contains 1 protein kinase domain.

Subcellular localization

Membrane;Single-pass type I membrane protein(By similarity).

Gene name

EPH receptor A4

Protein sequence

MAGIFYFALFSCLFGICDAVTGSRVYPANEVTLLDSRSVQ GELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPS QNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTC KETFNLYYYESDNDKERFIRENQFVKIDTIAADESFTQV DIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVS VRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVN NSEEKDVPKMYCGADGEWLVPIGNCLCNAGHEERSGECQ ACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGF FRADNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQ NTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHYTPQQN GLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSV SVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNG VILEYEVKYYEKDQNERSYRIVRTAARNTDIKGLNPLTS YVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANST VLLVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEE KHLNQGVRTYVDPFTYEDPNQAVREFAKEIDASCIKIEK VIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQR RDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYME NGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSY VHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTT RGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSY GERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLD CWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRP NTALLDPSSPEFSAVVSVGDWLQVIKMDRYKDNFTAAGYTTLEAVVHVNQE

Database cross reference

RefSeq Protein accession:NP_004429
RefSeq Protein gi:4758280

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0005887;C:integral to plasma membrane;IEA:InterPro.

GO-F

GO:0005524;F:ATP binding;IEA:UniProtKB-KW. GO:0005003;F:ephrin receptor activity;IEA:InterPro.

GO-P

GO:0006468;P:protein phosphorylation;IEA:InterPro. GO:0007169;P:transmembrane receptor protein tyrosine kinase signaling pathway;IEA:InterPro.

Pathway

Pathway name

IL2