Choose one of the five choices you want to search:

Gene, Transcriptome, Protein, Pathway or Disease. 

Protein basic information

LiverAtlas Protein ID

HuLPr34717

Uniprot ID

Q59H40_HUMAN

Uniprot Acc

Q59H40;

Protein name

Fibroblast growth factor receptor 1 isoform 1 variant

Comment

CATALYTIC ACTIVITY:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.||SIMILARITY:Contains 1 protein kinase domain.

Gene name

fibroblast growth factor receptor 1

Protein sequence

TRMAAVTRDFGEMLLHSGRVLPAEAQPWGAPVEVESFLVH PGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEE VEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPS SEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEK KLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHR IGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINH TYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVY SDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTT DKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTV LEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVY KMKSGTKKSDFHSQMAVHKLAKSIPLRRQVSADSSASMN SGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDR LVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKML KSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDG PLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQ LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTE DNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEAL FDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFK LLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQL VEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCS SGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR

Database cross reference

RefSeq Protein accession:NP_001167534
RefSeq Protein gi:291327489

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

Ontology annotation

GO-C

GO:0016021;C:integral to membrane;IEA:UniProtKB-KW.

GO-F

GO:0005524;F:ATP binding;IEA:UniProtKB-KW. GO:0005007;F:fibroblast growth factor receptor activity;IEA:InterPro.

GO-P

GO:0008284;P:positive regulation of cell proliferation;IEA:InterPro. GO:0006468;P:protein phosphorylation;IEA:InterPro.

Pathway

Pathway name

TCR