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Protein basic information

LiverAtlas Protein ID

HuLPr35445

Uniprot ID

Q5QPB7_HUMAN

Uniprot Acc

Q5QPB7;

Protein name

Hepatocyte nuclear factor 4, alpha

Comment

SIMILARITY:Belongs to the nuclear hormone receptor family.||SIMILARITY:Contains 1 nuclear receptor DNA-binding domain.

Gene name

hepatocyte nuclear factor 4, alpha

Protein sequence

MILLPLRLARLRHPLRHHWSISGGVDSSPQGDTSPSEGTN LNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRR SVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGM KKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQ ITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAK YIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDV LLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQI DDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLE DYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIK LFGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHLMQEHM GTNVIVANTMPTHLSNGQMCEWPRPRGQAATPETPQPSP PGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI

Database cross reference

RefSeq Protein accession:NP_000448
RefSeq Protein gi:31077205

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;French Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0005634;C:nucleus;IEA:UniProtKB-KW.

GO-F

GO:0043565;F:sequence-specific DNA binding;IEA:InterPro. GO:0003700;F:sequence-specific DNA binding transcription factor activity;IEA:InterPro. GO:0003707;F:steroid hormone receptor activity;IEA:InterPro. GO:0008270;F:zinc ion binding;IEA:InterPro.