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Gene, Transcriptome, Protein, Pathway or Disease. 

Protein basic information

LiverAtlas Protein ID

HuLPr36347

Uniprot ID

Q5VSQ6_HUMAN

Uniprot Acc

Q5VSQ6;

Protein name

Procollagen-proline, 2-oxoglutarate 4-dioxygenase (Proline 4-hydroxylase), alpha polypeptide I

Gene name

prolyl 4-hydroxylase, alpha polypeptide I

Protein sequence

MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVT SLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVG HPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQR QYFPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVK HKSFLTAEDCFELGKVAYTEADYYHTELWMEQALRQLDE GEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELD PEHQRANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPK KKGVAVDYLPERQKYEMLCRGEGIKMTPRRQKKLFCRYH DGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIV KDLAKPRLSRATVHDPETGKLTTAQYRVSKSAWLSGYEN PVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHF DFARKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFP EVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVG NKWVSNKWLHERGQEFRRPCTLSELE

Database cross reference

RefSeq Protein accession:NP_000908
RefSeq Protein gi:63252886

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0005581;C:collagen;IEA:UniProtKB-KW. GO:0005783;C:endoplasmic reticulum;IDA:HPA. GO:0005739;C:mitochondrion;IDA:HPA.

GO-F

GO:0005506;F:iron ion binding;IEA:InterPro. GO:0031418;F:L-ascorbic acid binding;IEA:InterPro. GO:0016702;F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;IEA:UniProtKB-KW. G

GO-P

GO:0055114;P:oxidation-reduction process;IEA:InterPro.