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Protein basic information

LiverAtlas Protein ID

HuLPr37316

Uniprot ID

Q6FHS8_HUMAN

Uniprot Acc

Q6FHS8;

Protein name

Uracil-DNA glycosylase

Comment

FUNCTION:Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity).||SIMILARITY:Belongs to the uracil-DNA glycosylase family.

Gene name

uracil-DNA glycosylase

Protein sequence

MGVFCLGPWGSGRKLRTPGKGPLQLLSRLCGDHLQAIPAK KAPAGQEEPGTPPSSPLSAEQLDRIQRNKAAALLRLAAR NVPVGFGESWKKHLSGEFGKPYFIKLMGFVVEERKHYTV YPPPHQVFTWTQMCDIKDVKVVILGQDPYHGPNQAHGLC FSVQRPVPPPPSLENIYKELSTDIEDFVHPGHGDLSGWA KQGVLLLNAVLTVRAHQANSHKERGWEQFTDAVVSWLNQ NSNGLVFLLWGSYAQKKGSAIDRKRHHVLQTAHPSPLSV YRGFFGCRHFSKTNELLQKSGKKPIDWKEL

Database cross reference

RefSeq Protein accession:NP_003353
RefSeq Protein gi:6224979

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

Ontology annotation

GO-C

GO:0005737;C:cytoplasm;IEA:HAMAP.

GO-F

GO:0004844;F:uracil DNA N-glycosylase activity;IEA:HAMAP.

GO-P

GO:0006284;P:base-excision repair;IEA:HAMAP.