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Protein basic information

LiverAtlas Protein ID

HuLPr37333

Uniprot ID

Q6FHX6_HUMAN

Uniprot Acc

Q6FHX6;

Protein name

FEN1 protein

Gene name

flap structure-specific endonuclease 1

Protein sequence

MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIY QFLIAVRQGGDVLQNEEGETTSHLMGMFYRTIRMMENGI KPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQAAG AEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPS EAEASCAALVKAGKVYAAATEDMDCLTFGSPVLMRHLTA SEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYC ESIRGIGPKRAVDLIQKHKSIEEIVRRLDPNKYPVPENW LHKEAHQLFLEPEVLDPESVELKWSEPNEEELIKFMCGE KQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGSLSS AKRKEPEPKGSTKKKAKTGAAGKFKRGK

Database cross reference

RefSeq Protein accession:NP_004102
RefSeq Protein gi:4758356

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0005634;C:nucleus;IDA:HPA.

GO-F

GO:0008409;F:5'-3' exonuclease activity;IEA:HAMAP. GO:0017108;F:5'-flap endonuclease activity;IEA:HAMAP. GO:0003677;F:DNA binding;IEA:HAMAP. GO:0000287;F:magnesium ion binding;IEA:HAMAP.

GO-P

GO:0006281;P:DNA repair;IEA:HAMAP. GO:0043137;P:DNA replication, removal of RNA primer;IEA:HAMAP.