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Protein basic information

LiverAtlas Protein ID

HuLPr37453

Uniprot ID

Q6I9V2_HUMAN

Uniprot Acc

Q6I9V2;

Protein name

ATP synthase gamma chain

Comment

FUNCTION:Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity).||SUBUNIT:F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits:alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits:a, b and c (By similarity).||SIMILARITY:Belongs to the ATPase gamma chain family.

Gene name

ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1

Protein sequence

MFSRAGVAGLSAWTLQPQWIQVRNMATLKDITRRLKSIKN IQKITKSMKMVAAAKYARAERELKPARIYGLGSLALYEK ADIKGPEDKKKHLLIGVSSDRGLCGAIHSSIAKQMKSEV ATLTAAGKEVMLVGIGDKIRGILYRTHSDQFLVAFKEVG RKPPTFGDASVIALELLNSGYEFDEGSIIFNKFRSVISY KTEEKPIFSLNTVASADSMSIYDDIDADVLQNYQEYNLA NIIYYSLKESTTSEQSARMTAMDNASKNASEMIDKLTLT FNRTRQAVITKELIEIISGAAALD

Database cross reference

RefSeq Protein accession:NP_001001973
RefSeq Protein gi:50345988

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;French Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0045261;C:proton-transporting ATP synthase complex, catalytic core F(1);IEA:UniProtKB-KW.

GO-F

GO:0046933;F:hydrogen ion transporting ATP synthase activity, rotational mechanism;IEA:InterPro. GO:0046961;F:proton-transporting ATPase activity, rotational mechanism;IEA:InterPro.

GO-P

GO:0015986;P:ATP synthesis coupled proton transport;IEA:InterPro.

Pathway

Pathway name

TCR