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Gene, Transcriptome, Protein, Pathway or Disease. 

Protein basic information

LiverAtlas Protein ID

HuLPr38029

Uniprot ID

Q6NWP6_HUMAN

Uniprot Acc

Q6NWP6;

Protein name

Interleukin 1 receptor, type I

Comment

SIMILARITY:Contains 1 TIR domain.

Gene name

interleukin 1 receptor, type I

Protein sequence

MKVLLRLICFIALLISSLEADKCKEREEKIILVSSANEID VRPCPLNPNEHKGTITWYKDDSKTPVSTEQASRIHQHKE KLWFVPAKVEDSGHYYCVVRNSSYCLRIKISAKFVENEP NLCYNAQAIFKQKLPVAGDGGLVCPYMEFFKNENNELPK LQWYKDCKPLLLDNIHFSGVKDRLIVMNVAEKHRGNYTR HASYTYLGKQYPITRVIEFITLEENKPTRPVIVSPANET MEVDLGSQIQLICNVTGQLSDIAYWKWNGSVIDEDDPVL GEDYYSVENPANKRRSTLITVLNISEIESRFYKHPFTCF AKNTHGIDAAYIQLIYPVTNFQKHMIGICVTLTVIIVCS VFIYKIFKIDIVLWYRDSCYDFLPIKASDGKTYDAYILY PKTVGEGSTSDCDIFVFKVLPGVLEKQCGYKLFIYGRDD YVGEDIVEVINENVKKSRRLIIILVRETSGFSWLGGSSE EQIAMYNALVQDGIKVVLLELEKIQDYEKMPESIKFIKQ KHGTIRWSGDFTQGPQSAKTRFWKNVRYHMPVQRRSPSS KHQLLSPATKEKLQREAHVPLG

Database cross reference

RefSeq Protein accession:NP_000868
RefSeq Protein gi:4504659

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

Ontology annotation

GO-C

GO:0016021;C:integral to membrane;IEA:UniProtKB-KW.

GO-F

GO:0004909;F:interleukin-1, Type I, activating receptor activity;IEA:InterPro.

GO-P

GO:0045087;P:innate immune response;IEA:InterPro.

Pathway

Pathway name

TCR

Pathway name

IL2

Pathway name

TGF_beta_Receptor