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Protein basic information

LiverAtlas Protein ID

HuLPr38138

Uniprot ID

Q6P453_HUMAN

Uniprot Acc

Q6P453;

Protein name

Ubiquitin carboxyl-terminal hydrolase

Comment

CATALYTIC ACTIVITY:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.||SIMILARITY:Belongs to the peptidase C19 family.

Gene name

ubiquitin specific peptidase 11

Protein sequence

RTAMATVAANPAAAAAAVAAAAAVTEDREPQHEELPGLDS QWRQIENGESGRERPLRAGESWFLVEKHWYKQWEAYVQG GDQDSSTFPGCINNATLFQDEINWRLKEGLVEGEDYVLL PAAAWHYLVSWYGLEHGQPPIERKVIELPNIQKVEVYPV ELLLVRHNDLGKSHTVQFSHTDSIGLVLRTARERFLVEP QEDTRLWAKNSEGSLDRLYDTHITVLDAALETGQLIIME TRKKDGTWPSAQLHVMNNNMSEEDEDFKGQPGICGLTNL GNTCFMNSALQCLSNVPQLTEYFLNNCYLEELNFRNPLG MKGEIAEAYADLVKQAWSGHHRSIVPHVFKNKVGHFASQ FLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYVELCDAA GRPDQEVAQEAWQNHKRRNDSVIVDTFHGLFKSTLVCPD CGNVSVTFDPFCYLSVPLPISHKRVLEVFFIPMDPRRKP EQHRLVVPKKGKISDLCVALSKHTGISPERMMVADVFSH RFYKLYQLEEPLSSILDRDDIFVYEVSGRIEAIEGSRED IVVPVYLRERTPARDYNNSYYGLMLFGHPLLVSVPRDRF TWEGLYNVLMYRLSRYVTKPNSDDEDDGDEKEDDEEDKD DVPGPSTGGSLRDPEPEQAGPSSGVTNRCPFLLDNCLGT SQWPPRRRRKQLFTLQTVNSNGTSDRTTSPEEVHAQPYI AIDWEPEMKKRYYDEVEAEGYVKHDCVGYVMKKAPVRLQ ECIELFTTVETLEKENPWYCPSCKQHQLATKKLDLWMLP EILIIHLKRFSYTKFSREKLDTLVEFPIRDLDFSEFVIQ PQNESNPELYKYDLIAVSNHYGGMRDGHYTTFACNKDSG QWHYFDDNSVSPVNENQIESKAAYVLFYQRQDVARRLLS PAGSSGAPASPACSSPPSSEFMDVN

Database cross reference

RefSeq Protein accession:NP_004642
RefSeq Protein gi:24234683

Liver relevance

HLPP validation

Yes/No

Yes

Project name

French Liver;Human Liver Organelles;

Ontology annotation

GO-F

GO:0008234;F:cysteine-type peptidase activity;IEA:UniProtKB-KW. GO:0004221;F:ubiquitin thiolesterase activity;IEA:EC.

GO-P

GO:0006511;P:ubiquitin-dependent protein catabolic process;IEA:InterPro.