Choose one of the five choices you want to search:

Gene, Transcriptome, Protein, Pathway or Disease. 

Protein basic information

LiverAtlas Protein ID

HuLPr38483

Uniprot ID

Q6RR12_HUMAN

Uniprot Acc

Q6RR12;

Protein name

NADH-ubiquinone oxidoreductase chain 1

Comment

CATALYTIC ACTIVITY:NADH + ubiquinone = NAD(+) + ubiquinol.||SUBCELLULAR LOCATION:Membrane; Multi-pass membrane protein (By similarity).||SIMILARITY:Belongs to the complex I subunit 1 family.

Subcellular localization

Membrane;Multi-pass membrane protein(By similarity).

Gene name

NADH dehydrogenase, subunit 1 (complex I)

Protein sequence

MPMANLLLLIVPILIAMAFLMLTERKILGYMQLRKGPNVV GPYGLLQPFADAMKLFTKEPLKPATSTIALYITAPTLAL TIALLLWTPLPMPNPLVNLNLGLLFILATSSLAVYSILW SGWASNSNYALIGALRAVAQTISYEVTLAIILLSTLLMS GSFNLSTLITTQEHLWLLLPSWPLAMMWFISTLAETNRT PFDLAEGESELVSGFNIEYAAGPFALFFMAEYTNIIMMN TLTTTIFLGTTYDALSPELYTTYFVTKTLLLTSLFLWIR TAYPRFRYDQLMHLLWKNFLPLTLALLMWYVSMPITISSIPPQT

Database cross reference

RefSeq Protein accession:YP_003024026
RefSeq Protein gi:251831107

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0016021;C:integral to membrane;IEA:UniProtKB-KW. GO:0005739;C:mitochondrion;IEA:UniProtKB-KW.

GO-F

GO:0008137;F:NADH dehydrogenase (ubiquinone) activity;IEA:EC.