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Gene, Transcriptome, Protein, Pathway or Disease. 

Protein basic information

LiverAtlas Protein ID

HuLPr40174

Uniprot ID

Q86WY9_HUMAN

Uniprot Acc

Q86WY9;

Protein name

INSR protein

Gene name

insulin receptor

Protein sequence

AATPLLVAVAALLLGAAGHLYPGEVCPGMDIRNNLTRLHE LENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYL LLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVH LKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDS VEDNYIVLNKDDNEECGDICPGTAKGKTNCPATVINGQF VERCWTHSHCQKVCPTICKSHGCNAEGLCCHSECLGNCS QPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNF SLCQDLHHKCKNSRRQGCHQYVIHNNKCIPECPSGYTMN SSNLLCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGCT VINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRS YALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLW DWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGR QERNDIALKTNGDQASCENELLKFSYIRTSFDKILLRWE PYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSW TVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKT LVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNS SSQIILKWKPPSDPNGNITHYLVFWERQAEDSELFELDY CLKGLKLPSRTWSPPFESEDSQKHNQSEYEDSAGECCSC PKTDSQILKELEESSFRKTFEDYLHNVVFVPRSGLGAGLS

Database cross reference

RefSeq Protein accession:NP_000199
RefSeq Protein gi:119395736

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;

Ontology annotation

GO-C

GO:0016020;C:membrane;IEA:InterPro.

GO-F

GO:0005524;F:ATP binding;IEA:InterPro. GO:0004714;F:transmembrane receptor protein tyrosine kinase activity;IEA:InterPro.

GO-P

GO:0007169;P:transmembrane receptor protein tyrosine kinase signaling pathway;IEA:InterPro.

Pathway

Pathway name

TGF_beta_Receptor