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Protein basic information

LiverAtlas Protein ID

HuLPr40417

Uniprot ID

Q8IVZ4_HUMAN

Uniprot Acc

Q8IVZ4;

Protein name

ABCC4 protein

Comment

SIMILARITY:Belongs to the ABC transporter superfamily.

Gene name

ATP-binding cassette, sub-family C (CFTR/MRP), member 4

Protein sequence

MLPVYQEVKPNPLQDANLCSRVFFWWLNPLFKIGHKRRLE EDDMYSVLPEDRSQHLGEELQGFWDKEVLRAENDAQKPS LTRAIIKCYWKSYLVLGIFTLIEESAKVIQPIFLGKIIN YFENYDPMDSVALNTAYAYATVLTFCTLILAILHHLYFY HVQCAGMRLRVAMCHMIYRKALRLSNMAMGKTTTGQIVN LLSNDVNKFDQVTVFLHFLWAGPLQAIAVTALLWMEIGI SCLAGMAVLIILLPLQSCFGKLFSSLRSKTATFTDARIR TMNEVITGIRIIKMYAWEKSFSNLITNLRKKEISKILRS SCLRGMNLASFFSASKIIVFVTFTTYVLLGSVITASRVF VAVTLYGAVRLTVTLFFPSAIERVSEAIVSIRRIQTFLL LDEISQRNRQLPSDGKKMVHVQDFTAFWDKASETPTLQG LSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHGLV SVHGRIAYVSQQPWVFSGTLRSNILFGKKYEKERYEKVI KACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLAR AVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHEKI TILVTHQLQYLKAASQILILKDGKMVQKGTYTEFLKSGI DFGSLLKKDNEESEQPPVPGTPTLRNRTFSESSVWSQQS SRPSLKDGALESQDTENVPVTLSEENRSEGKVGFQAYKN YFRAGAHWIVFIFLILLNTAAQVAYVLQDWWLSYWANKQ SMLNVTVNGGGNVTEKLDLNWYLGIYSGLTVATVLFGIA RSLLVFYVLVNSSQTLHNKMFESILKAPVLFFDRNPIGR ILNRFSKDIGHLDDLLPLTFLDFIQRWDLAVLSWLVSNS

Database cross reference

RefSeq Protein accession:NP_001098985
RefSeq Protein gi:157502203

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

Ontology annotation

GO-C

GO:0016021;C:integral to membrane;IEA:InterPro.

GO-F

GO:0005524;F:ATP binding;IEA:UniProtKB-KW. GO:0042626;F:ATPase activity, coupled to transmembrane movement of substances;IEA:InterPro. GO:0005254;F:chloride channel activity;IEA:InterPro.

Pathway

Pathway name

IL6