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Protein basic information

LiverAtlas Protein ID

HuLPr40795

Uniprot ID

Q8N6H3_HUMAN

Uniprot Acc

Q8N6H3;

Protein name

Aminolevulinate, delta-, synthase 2

Comment

COFACTOR:Pyridoxal phosphate (By similarity).||SIMILARITY:Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

Gene name

aminolevulinate, delta-, synthase 2

Protein sequence

MRGGEVALGWNKKKRLFCEDFRFKMVTAAMLLQCCPVLAR GPTSLLGKVVKTHQFLFGIGRCPILATQGPNCSQIHLKA TKAGGDSPSWAKGHCPFMLSELQDGKSKIVQKAAPEVQE DVKAFKTGNYVFSYDQFFRDKIMEKKQDHTYRVFKTVNR WADAYPFAQHFSEASVASKDVSVWCSNDYLGMSRHPQVL QATQETLQRHGVGAGGTRNISGTSKFHVELEQELAELHQ KDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHAS MIQGIRNSGAAKFVFRHNDPDHLKKLLEKSNPKIPKIVA FETVHSMDGAICPLEELCDVSHQYGALTFVDEVHAVGLY GSRGAGIGERDGIMHKIDIISGTLGKAFGCVGGYIASTR DLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEG QALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRVGN AALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLRLAPS PHHSPQMMEDFVEKLLLAWTAVGLPLQDVSVAACNFCRR PVHFELMSEWERSYFGNMGPQYVTTYA

Database cross reference

RefSeq Protein accession:NP_000023
RefSeq Protein gi:83977442

Liver relevance

HLPP validation

Yes/No

Yes

Project name

French Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0005759;C:mitochondrial matrix;IEA:InterPro.

GO-F

GO:0003870;F:5-aminolevulinate synthase activity;IEA:InterPro. GO:0030170;F:pyridoxal phosphate binding;IEA:InterPro. GO:0016769;F:transferase activity, transferring nitrogenous groups;IEA:InterPro.

GO-P

GO:0006778;P:porphyrin metabolic process;IEA:InterPro. GO:0033014;P:tetrapyrrole biosynthetic process;IEA:InterPro.