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Protein basic information

LiverAtlas Protein ID

HuLPr41090

Uniprot ID

Q8NE26_HUMAN

Uniprot Acc

Q8NE26;

Protein name

ADAM metallopeptidase with thrombospondin type 1 motif, 1

Comment

SIMILARITY:Contains 1 disintegrin domain.||SIMILARITY:Contains 1 peptidase M12B domain.

Gene name

ADAM metallopeptidase with thrombospondin type 1 motif, 1

Protein sequence

MQRAVPEGFGRRKLGSDMGNAERAPGSRSFGPVPTLLLLA AALLAVSDALGRPSEEDEELVVPELERAPGHGTTRLRLH AFDQQLDLELRPDSSFLAPGFTLQNVGRKSGSETPLPET DLAHCFYSGTVNGDPSSAAALSLCEGVRGAFYLLGEAYF IQPLPAASERLATAAPGEKPPAPLQFHLLRRNRQGDVGG TCGVVDDEPRPTGKAETEDEDEGTEGEDEGPQWSPQDPA LQGVGQPTGTGSIRKKRFVSSHRYVETMLVADQSMAEFH GSGLKHYLLTLFSVAARLYKHPSIRNSVSLVVVKILVIH DEQKGPEVTSNAALTLRNFCNWQKQHNPPSDRDAEHYDT AILFTRQDLCGSQTCDTLGMADVGTVCDPSRSCSVIEDD GLQAAFTTAHELGHVFNMPHDDAKQCASLNGVNQDSHMM ASMLSNLDHSQPWSPCSAYMITSFLDNGHGECLMDKPQN PIQLPGDLPGTSYDANRQCQFTFGEDSKHCPDAASTCST LWCTGTSGGVLVCQTKHFPWADGTSCGEGKWCINGKCVN KTDRKHFDTPFHGSWGMWGPWGDCSRTCGGGVQYTMREC DNPVPKNGGKYCEGKRVRYRSCNLEDCPDNNGKTFREEQ CEAHNEFSKASFGSGPAVEWIPKYAGVSPKDRCKLICQA KGIGYFFVLQPKVVDGTPCSTDSTSVCVQGQCVKAGCDR IIDSKKKFDKCGVCGGNGSTCKKISGSVTSAKPGYHDII TIPTGATNIEVKQRNQRGSRNNGSFLAIKAADGTYILNG DYTLSTLEQDIMYKGVVLRYSGSSAALERIRSFSPLKEP LTIQVLTVGNALRPKIKYTYFVKKKKESFNAIPTFSAWV IEEWGECSKSCELGWQRRLVECRDINGQPASECAKEVKP ASTRPCADHPCPQWQLGEWSSCSKTCGKGYKKRSLKCLS HDGGVLSHESCDPLKKPKHFIDFCTMAECS

Database cross reference

RefSeq Protein accession:NP_008919
RefSeq Protein gi:50845384

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;French Liver;

Ontology annotation

GO-C

GO:0005578;C:proteinaceous extracellular matrix;IEA:InterPro.

GO-F

GO:0004222;F:metalloendopeptidase activity;IEA:InterPro. GO:0008270;F:zinc ion binding;IEA:InterPro.

GO-P

GO:0006508;P:proteolysis;IEA:InterPro.

Pathway

Pathway name

TSH

Pathway name

TGF_beta_Receptor