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Protein basic information

LiverAtlas Protein ID

HuLPr41640

Uniprot ID

Q8WYK4_HUMAN

Uniprot Acc

Q8WYK4;

Protein name

Thymidylate synthase

Comment

CATALYTIC ACTIVITY:5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP.||PATHWAY:Pyrimidine metabolism; dTTP biosynthesis.||SIMILARITY:Belongs to the thymidylate synthase family.

Gene name

actin, alpha 2, smooth muscle, aorta

Protein sequence

MPVAGSELPRRPLPPAAQERDAEPRPPHGELQYLGQIQHI LRCGVRKDDRTGTGTLSVFGMQARYSLRDYSGQGVDQLQ RVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQF YVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHI TGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKL RILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV

Database cross reference

RefSeq Protein accession:NP_001135417
RefSeq Protein gi:213688375

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;

Ontology annotation

GO-F

GO:0004799;F:thymidylate synthase activity;IEA:EC.

GO-P

GO:0006231;P:dTMP biosynthetic process;IEA:InterPro.