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Protein basic information

LiverAtlas Protein ID

HuLPr42057

Uniprot ID

Q96L35_HUMAN

Uniprot Acc

Q96L35;

Protein name

Ephrin receptor

Comment

CATALYTIC ACTIVITY:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.||SUBCELLULAR LOCATION:Membrane; Single-pass type I membrane protein (By similarity).||SIMILARITY:Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.||SIMILARITY:Contains 1 SAM (sterile alpha motif) domain.||SIMILARITY:Contains 1 protein kinase domain.

Subcellular localization

Membrane;Single-pass type I membrane protein(By similarity).

Gene name

EPH receptor B4

Protein sequence

MELRVLLCWASLAAALEETLLNTKLETADLKWVTFPQVDG QWEELSGLDEEQHSVRTYEVCDVQRAPGQAHWLRTGWVP RRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYES DADTATALTPAWMENPYIKVDTVAAEHLTRKRPGAEATG KVNVKTLRLGPLSKAGFYLAFQDQGACMALLSLHLFYKK CAQLTVNLTRFPETVPRELVVPVAGSCVVDAVPAPGPSP SLYCREDGQWAEQPVTGCSCAPGFEAAEGNTKCRACAQG TFKPLSGEGSCQPCPANSHSNTIGSAVCQCRVGYFRART DPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGR EDLTYALRCRECRPGGSCAPCGGDLTFDPGPRDLVEPWV VVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNVTTD REVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEV KYHEKGAEGPSSVRFLKTSENRAELRGLKRGASYLVQVR ARSEAGYGPFGQEHHSQTQLDESEGWREQLALIAGTAVV GVVLVLVVIVVAVLCLRKQSNGREAEYSDKHGQYLIGHG TKVYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGE FGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSE ASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDS FLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLA ARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGK IPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERP YWDMSNQDVINAIEQDYRLPPPPDCPTSLHQLMLDCWQK DRNARPRFPQVVSALDKMIRNPASLKIVARENGGDLLRI GVTLAGHQKKILASVQHMKSQAKPGTPGGTGGPAPQY

Database cross reference

RefSeq Protein accession:NP_004435
RefSeq Protein gi:32528301

Ontology annotation

GO-C

GO:0005887;C:integral to plasma membrane;IEA:InterPro.

GO-F

GO:0005524;F:ATP binding;IEA:UniProtKB-KW. GO:0005003;F:ephrin receptor activity;IEA:InterPro.

GO-P

GO:0006468;P:protein phosphorylation;IEA:InterPro. GO:0007169;P:transmembrane receptor protein tyrosine kinase signaling pathway;IEA:InterPro.