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Protein basic information

LiverAtlas Protein ID

HuLPr43644

Uniprot ID

Q9UII8_HUMAN

Uniprot Acc

Q9UII8;

Protein name

Cadherin 1, type 1, E-cadherin (Epithelial), isoform CRA c

Comment

FUNCTION:Cadherins are calcium dependent cell adhesion proteins (By similarity).||SUBCELLULAR LOCATION:Membrane; Single-pass type I membrane protein (By similarity).

Subcellular localization

Membrane;Single-pass type I membrane protein(By similarity).

Gene name

cadherin 1, type 1, E-cadherin (epithelial)

Protein sequence

MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFT VPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGT DGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNT VGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWV IPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQG ADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAV SSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEG ALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPD KNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQG EGLSTTATAVITVTDTNDNPPIFNPTTGLDFEAKQQYIL HVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEK RVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTA NWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATD NGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPK PQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQ ESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVC DCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILIL LLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEED QDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPAN PDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEA ASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD

Database cross reference

RefSeq Protein accession:NP_004351
RefSeq Protein gi:4757960

Liver relevance

HLPP validation

Yes/No

Yes

Project name

French Liver;Human Fetal Liver;

Ontology annotation

GO-C

GO:0016235;C:aggresome;IDA:HPA. GO:0005737;C:cytoplasm;IDA:HPA. GO:0005925;C:focal adhesion;IDA:HPA. GO:0016021;C:integral to membrane;IEA:UniProtKB-KW.

GO-F

GO:0005509;F:calcium ion binding;IEA:InterPro.

GO-P

GO:0007156;P:homophilic cell adhesion;IEA:InterPro.