Protein basic information
| LiverAtlas Protein ID |
HuLPr44181 |
|
Uniprot ID |
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|
Uniprot Acc |
P53805;D3DSF9;O00582;O00583;Q53XT0;Q6IBC6;Q7Z555;Q96R03;Q9BU69;Q9UF15;Q9UME4; |
|
Protein name |
Calcipressin-1 |
|
Comment |
FUNCTION:Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=4; Name=1; IsoId=P53805-1; Sequence=Displayed; Name=2; IsoId=P53805-2; Sequence=VSP 001314; Name=3; IsoId=P53805-3; Sequence=VSP 001315; Name=4; IsoId=P53805-4; Sequence=VSP 001316;||TISSUE SPECIFICITY:Highly expressed heart, brain and skeletal muscle. Also expressed in all other tissues.||INDUCTION:By calcium.||SIMILARITY:Belongs to the RCAN family.||WEB RESOURCE:Name=GeneReviews; URL="http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/RCAN1"; |
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Gene name |
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Protein sequence
|
MEDGVAGPQLGAAAEAAEAAEARARPGVTLRPFAPLSGAA EADEGGGDWSFIDCEMEEVDLQDLPSATIACHLDPRVFV DGLCRAKFESLFRTYDKDITFQYFKSFKRVRINFSNPFS AADARLQLHKTEFLGKEMKLYFAQTLHIGSSHLAPPNPD KQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPG EKYELHAATDTTPSVVVHVCESDQEKEEEEEMERMRRPK PKIIQTRRPEYTPIHLS |
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Database cross reference |
RefSeq Protein accession:NP_004405
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Liver relevance
|
HLPP validation |
Yes/No |
Yes |
|
Project name |
Chinese Liver;Human Liver Organelles; |
Ontology annotation
| GO-C |
GO:0005634;C:nucleus;TAS:ProtInc. |
|
GO-F |
GO:0003677;F:DNA binding;TAS:ProtInc. GO:0005515;F:protein binding;IPI:IntAct. GO:0003700;F:sequence-specific DNA binding transcription factor activity;TAS:ProtInc. |
|
GO-P |
GO:0008015;P:blood circulation;TAS:ProtInc. GO:0019722;P:calcium-mediated signaling;IEA:InterPro. GO:0007417;P:central nervous system development;TAS:ProtInc. |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
|
HuLPr44181 |
PHOSPHORYLATION |
108 |
S |
Phospho-ELM |
LTP |
N |
 
|
|
|
HuLPr44181 |
PHOSPHORYLATION |
112 |
S |
Phospho-ELM |
LTP |
N |
|
|
|
HuLPr44181 |
PHOSPHORYLATION |
163 |
S |
PhosphoSitePlus |
LTP HTP |
N |
|
|
|
HuLPr44181 |
PHOSPHORYLATION |
167 |
S |
PhosphoSitePlus |
LTP HTP |
N |
|
|
|
HuLPr44181 |
PHOSPHORYLATION |
94 |
Y |
PhosphoSitePlus |
LTP |
N |
|
Pathway
| Pathway name | |
| Pathway name | |
| Pathway name | |
| Pathway name |
