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Protein basic information

LiverAtlas Protein ID

HuLPr44654

Uniprot ID

RNAS4_HUMAN

Uniprot Acc

P34096;

Protein name

Ribonuclease 4

Comment

FUNCTION:This RNase has marked specificity towards the 3' side of uridine nucleotides.||SUBCELLULAR LOCATION:Secreted.||SIMILARITY:Belongs to the pancreatic ribonuclease family.

Subcellular localization

Secreted.

Gene name

ribonuclease, RNase A family, 4

Related liver disease name

Hepatocellular carcinoma

Protein sequence

MALQRTHSLLLLLLLTLLGLGLVQPSYGQDGMYQRFLRQH VHPEETGGSDRYCNLMMQRRKMTLYHCKRFNTFIHEDIW NIRSICSTTNIQCKNGKMNCHEGVVKVTDCRDTGSSRAP NCRYRAIASTRRVVIACEGNPQVPVHFDG

Database cross reference

RefSeq Protein accession:NP_002928
RefSeq Protein gi:4506557

Liver relevance

HCC significant Proteins

Yes/No

Yes

Quality score

Ontology annotation

GO-C

GO:0005576;C:extracellular region;IEA:UniProtKB-SubCell.

GO-F

GO:0003676;F:nucleic acid binding;IEA:InterPro. GO:0004522;F:pancreatic ribonuclease activity;NAS:UniProtKB.

GO-P

GO:0006379;P:mRNA cleavage;NAS:UniProtKB.