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Protein basic information

LiverAtlas Protein ID

HuLPr44940

Uniprot ID

RUFY2_HUMAN

Uniprot Acc

Q8WXA3;B3KXB2;Q5TC48;Q8IW33;Q96P51;Q9P1Z1;

Protein name

RUN and FYVE domain-containing protein 2

Comment

SUBUNIT:Interacts with BMX.||SUBCELLULAR LOCATION:Nucleus (By similarity).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=4; Name=1; IsoId=Q8WXA3-1; Sequence=Displayed; Name=2; IsoId=Q8WXA3-2; Sequence=VSP 019788; Note=No experimental confirmation available; Name=3; IsoId=Q8WXA3-3; Sequence=VSP 040463; Name=4; IsoId=Q8WXA3-4; Sequence=VSP 019788, VSP 040464, VSP 040465, VSP 040466;||TISSUE SPECIFICITY:Expressed in brain, lung and testis.||SIMILARITY:Contains 1 FYVE-type zinc finger.||SIMILARITY:Contains 1 RUN domain.||SEQUENCE CAUTION:Sequence=CAI17232.1; Type=Erroneous gene model prediction;

Subcellular localization

Nucleus(By similarity).

Gene name

RUN and FYVE domain containing 2

Protein sequence

MGGDCLGLGGSRGRHGNAPPPLFRPVPARVLRHSGRGLEV PRRPGARTGPATKDPTAVERANLLNMAKLSIKGLIESAL SFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSYNK TIWGPLELVEKLYPEAEEIGASVRDLPGLKTPLGRARAW LRLALMQKKMADYLRCLIIQRDLLSEFYEYHALMMEEEG AVIVGLLVGLNVIDANLCVKGEDLDSQVGVIDFSMYLKN EEDIGNKERNVQIAAILDQKNYVEELNRQLNSTVSSLHS RVDSLEKSNTKLIEELAIAKNNIIKLQEENHQLRSENKL ILMKTQQHLEVTKVDVETELQTYKHSRQGLDEMYNEARR QLRDESQLRQDVENELAVQVSMKHEIELAMKLLEKDIHE KQDTLIGLRQQLEEVKAINIEMYQKLQGSEDGLKEKNEI IARLEEKTNKITAAMRQLEQRLQQAEKAQMEAEDEDEKY LQECLSKSDSLQKQISQKEKQLVQLETDLKIEKEWRQTL QEDLQKEKDALSHLRNETQQIISLKKEFLNLQDENQQLK KIYHEQEQALQELGNKLSESKLKIEDIKEANKALQGLVW LKDKEATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDN ELPLPSSPKPVRVCDSCHALLIQRCSSNLP

Database cross reference

RefSeq Protein accession:NP_001035882
RefSeq Protein gi:109240552

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0005634;C:nucleus;IEA:UniProtKB-SubCell.

GO-F

GO:0008270;F:zinc ion binding;IEA:InterPro.

Post-translational modification

LiverAtlas Protein ID

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr44940

PHOSPHORYLATION

631

S

Phospho-ELM

41901

HTP

N

HuLPr44940

PHOSPHORYLATION

507

T

PhosphoSitePlus

7104917

HTP

N

HuLPr44940

PHOSPHORYLATION

270

S

PhosphoSitePlus

5888218

HTP

N

HuLPr44940

PHOSPHORYLATION

271

S

PhosphoSitePlus

5888223

HTP

N

HuLPr44940

PHOSPHORYLATION

278

S

PhosphoSitePlus

5888228

HTP

N