Protein basic information
| LiverAtlas Protein ID |
HuLPr45057 |
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Uniprot ID |
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Uniprot Acc |
Q9Y6Y8;D3DRD2;Q8IXH5;Q9BUK5; |
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Protein name |
SEC23-interacting protein |
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Comment |
FUNCTION:Plays a role in the organization of endoplasmic reticulum exit sites.||SUBUNIT:Interacts with SEC23A.||SUBCELLULAR LOCATION:Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum (Probable).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9Y6Y8-1; Sequence=Displayed; Name=2; IsoId=Q9Y6Y8-2; Sequence=VSP 011831, VSP 011832; Note=No experimental confirmation available;||TISSUE SPECIFICITY:Ubiquitously expressed with stronger levels detected in heart, liver and skeletal muscle.||SIMILARITY:Belongs to the PA-PLA1 family.||SIMILARITY:Contains 1 DDHD domain.||SIMILARITY:Contains 1 SAM (sterile alpha motif) domain.||CAUTION:Although belonging to the PA-PL1 family, does not seem to have any phospholipase activity.||SEQUENCE CAUTION:Sequence=AAP35401.1; Type=Frameshift; Positions=471; |
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Subcellular localization |
Cytoplasmic vesicle, COPII-coated vesicle membrane;Peripheral membrane protein;Cytoplasmic side.Endoplasmic reticulum(Probable). |
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Gene name |
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Protein sequence
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MAERKPNGGSGGASTSSSGTNLLFSSSATEFSFNVPFIPV TQASASPASLLLPGEDSTDVGEEDSFLGQTSIHTSAPQT FSYFSQVSSSSDPFGNIGQSPLTTAATSVGQSGFPKPLT ALPFTTGSQDVSNAFSPSISKAQPGAPPSSLMGINSYLP SQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYI APPQLQQCQTPGPPAHPPPSGPPVQMYQMPPGSLPPVPS SVQSPAQQQVPARPGAPSVQVPSPFLLQNQYEPVQPHWF YCKEVEYKQLWMPFSVFDSLNLEEIYNSVQPDPESVVLG TDGGRYDVYLYDRIRKAAYWEEEPAEVRRCTWFYKGDTD SRFIPYTEEFSEKLEAEYKKAVTTNQWHRRLEFPSGETI VMHNPKVIVQFQPSSVPDEWGTTQDGQTRPRVVKRGIDD NLDEIPDGEMPQVDHLVFVVHGIGPVCDLRFRSIIECVD DFRVVSLKLLRTHFKKSLDDGKVSRVEFLPVHWHSSLGG DATGVDRNIKKITLPSIGRFRHFTNETLLDILFYNSPTY CQTIVEKVGMEINHLHALFMSRNPDFKGGVSVAGHSLGS LILFDILSNQKDLNLSKCPGPLAVANGVVKQLHFQEKQM PEEPKLTLDESYDLVVENKEVLTLQETLEALSLSEYFST FEKEKIDMESLLMCTVDDLKEMGIPLGPRKKIANFVEHK AAKLKKAASEKKAVAATSTKGQEQSAQKTKDMASLPSES NEPKRKLPVGACVSSVCVNYESFEVGAGQVSVAYNSLDF EPEIFFALGSPIAMFLTIRGVDRIDENYSLPTCKGFFNI YHPLDPVAYRLEPMIVPDLDLKAVLIPHHKGRKRLHLEL KESLSRMGSDLKQGFISSLKSAWQTLNEFARAHTSSTQL QEELEKVANQIKEEEEKQVVEAEKVVESPDFSKDEDYLG KVGMLNGGRRIDYVLQEKPIESFNEYLFALQSHLCYWES EDTALLLLKEIYRTMNISPEQPQH |
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Database cross reference |
RefSeq Protein accession:NP_009121
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Liver relevance
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HLPP validation |
Yes/No |
Yes |
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Project name |
Chinese Liver;Human Liver Organelles; |
Ontology annotation
| GO-C |
GO:0005783;C:endoplasmic reticulum;IEA:UniProtKB-SubCell. GO:0012507;C:ER to Golgi transport vesicle membrane;IEA:UniProtKB-SubCell. GO:0005793;C:ER-Golgi intermediate compartment;TAS:ProtInc. |
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GO-F |
GO:0046872;F:metal ion binding;IEA:InterPro. |
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GO-P |
GO:0007030;P:Golgi organization;TAS:ProtInc. GO:0006886;P:intracellular protein transport;TAS:ProtInc. |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
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HuLPr45057 |
PHOSPHORYLATION |
926 |
S |
Phospho-ELM |
HTP |
N |
 
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HuLPr45057 |
PHOSPHORYLATION |
648 |
T |
PhosphoSitePlus |
HTP |
N |
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HuLPr45057 |
PHOSPHORYLATION |
742 |
S |
PhosphoSitePlus |
HTP |
N |
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|
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HuLPr45057 |
PHOSPHORYLATION |
935 |
Y |
PhosphoSitePlus |
LTP |
N |
|
|
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HuLPr45057 |
PHOSPHORYLATION |
637 |
Y |
PhosphoSitePlus |
HTP |
N |
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HuLPr45057 |
PHOSPHORYLATION |
926 |
S |
PhosphoSitePlus |
LTP |
N |
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