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Protein basic information

LiverAtlas Protein ID

HuLPr45522

Uniprot ID

SFXN4_HUMAN

Uniprot Acc

Q6P4A7;Q6WSU4;Q86TD9;

Protein name

Sideroflexin-4

Comment

FUNCTION:Potential iron transporter (By similarity).||SUBCELLULAR LOCATION:Mitochondrion membrane; Multi-pass membrane protein (By similarity).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q6P4A7-1; Sequence=Displayed; Name=2; IsoId=Q6P4A7-2; Sequence=VSP 014609, VSP 014610; Note=No experimental confirmation available; Name=3; IsoId=Q6P4A7-3; Sequence=VSP 014608; Note=No experimental confirmation available;||SIMILARITY:Belongs to the sideroflexin family.

Subcellular localization

Mitochondrion membrane;Multi-pass membrane protein(By similarity).

Gene name

sideroflexin 4

Protein sequence

MSLEQEEETQPGRLLGRRDAVPAFIEPNVRFWITERQSFI RRFLQWTELLDPTNVFISVESIENSRQLLCTNEDVSSPA SADQRIQEAWKRSLATVHPDSSNLIPKLFRPAAFLPFMA PTVFLSMTPLKGIKSVILPQVFLCAYMAAFNSINGNRSY TCKPLERSLLMAGAVASSTFLGVIPQFVQMKYGLTGPWI KRLLPVIFLVQASGMNVYMSRSLESIKGIAVMDKEGNVL GHSRIAGTKAVRETLASRIVLFGTSALIPEVFTYFFKRT QYFRKNPGSLWILKLSCTVLAMGLMVPFSFSIFPQIGQI QYCSLEEKIQSPTEETEIFYHRGV

Database cross reference

RefSeq Protein accession:NP_998814
RefSeq Protein gi:47458811

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

Ontology annotation

GO-C

GO:0016021;C:integral to membrane;IEA:UniProtKB-KW. GO:0031966;C:mitochondrial membrane;IEA:UniProtKB-SubCell.

GO-F

GO:0008324;F:cation transmembrane transporter activity;IEA:InterPro.

GO-P

GO:0055072;P:iron ion homeostasis;IEA:UniProtKB-KW.

Post-translational modification

LiverAtlas Protein ID

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr45522

ACETYLATION

197

K

PhosphoSitePlus

11317395

HTP

N