HuLPr45731

Uniprot ID

SLIK2_HUMAN

Uniprot Acc

Q9H156;A8K117;Q2KHN3;Q5JXB1;Q8NBC7;Q96JH3;

Protein name

SLIT and NTRK-like protein 2

Comment

FUNCTION:Suppresses neurite outgrowth (By similarity).||SUBCELLULAR LOCATION:Membrane; Single-pass type I membrane protein (Potential).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9H156-1; Sequence=Displayed; Name=2; IsoId=Q9H156-2; Sequence=VSP 050706, VSP 050707; Note=No experimental confirmation available;||TISSUE SPECIFICITY:Expressed predominantly in the cerebral cortex of the brain but also at low levels in the spinal cord and medulla. Also expressed in some astrocytic brain tumors such as astrocytomas, oligodendrogliomas, glioblastomas, gangliogliomas and primitive neuroectodermal tumors.||SIMILARITY:Belongs to the SLITRK family.||SIMILARITY:Contains 12 LRR (leucine-rich) repeats.||SIMILARITY:Contains 2 LRRCT domains.||SIMILARITY:Contains 1 LRRNT domain.||SEQUENCE CAUTION:Sequence=BAB47483.1; Type=Erroneous initiation;

Subcellular localization

Membrane;Single-pass type I membrane protein(Potential).

Gene name

SLIT and NTRK-like family, member 2

Protein sequence

MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKEN VLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYP NEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLN NNKLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKL NKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVM PFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTIT VFVGEIVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQR GSHADTHVQRLSPTMNPALNPTRAPKASRPPKMRNRPTP RVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSD NGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVY KNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYL NGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDA LINLQLLFLNNNLLRSLPDNIFGGTALTRLNLRNNHFSH LPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHA NSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSD GTVLSMNHNTDTPRSLSVSPSSYPELHTEVPLSVLILGL LVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNLDVSS FQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQ KEGDPVAYYRNLQEFSYSNLEEKKEEPATPAYTISATEL LEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLPK RQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHP LLQAKPQSEPDYLEVLEKQTAISQL

Database cross reference

RefSeq Protein accession:NP_001137475
RefSeq Protein gi:221136957

HLPP validation

Yes/No

Yes

Project name

Human Fetal Liver;

GO:0016021;C:integral to membrane;IEA:UniProtKB-KW.

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr45731

PHOSPHORYLATION

3

S

PhosphoSitePlus

2526802

LTP

N

HuLPr45731

PHOSPHORYLATION

9

S

PhosphoSitePlus

2526805

HTP

N

HuLPr45731

PHOSPHORYLATION

588

T

PhosphoSitePlus

2526808

HTP

N