Protein basic information
| LiverAtlas Protein ID |
HuLPr45751 |
|
Uniprot ID |
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Uniprot Acc |
Q9NWH9;B2RTX3;Q2VPK7;Q52MB3;Q658J7;Q6ZNF2;Q86TK6;Q9H7C3;Q9H8U9; |
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Protein name |
SAFB-like transcription modulator |
|
Comment |
FUNCTION:When overexpressed, acts as a general inhibitor of transcription that eventually leads to apoptosis (By similarity).||SUBCELLULAR LOCATION:Nucleus (By similarity). Note=Detected in punctate structures (By similarity).||PTM:Phosphorylated upon DNA damage, probably by ATM or ATR (By similarity).||SIMILARITY:Contains 1 RRM (RNA recognition motif) domain.||SIMILARITY:Contains 1 SAP domain.||SEQUENCE CAUTION:Sequence=AAI08657.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence; Sequence=BAB14502.1; Type=Erroneous initiation; Sequence=BAB14971.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAB14971.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence; |
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Subcellular localization |
Nucleus(By similarity). |
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Gene name |
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Protein sequence
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MAAATGAVAASAASGQAEGKKITDLRVIDLKSELKRRNLD ITGVKTVLISRLKQAIEEEGGDPDNIELTVSTDTPNKKP TKGKGKKHEADELSGDASVEDDAFIKDCELENQEAHEQD GNDELKDSEEFGENEEENVHSKELLSAEENKRAHELIEA EGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEK DIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTV KEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDS EASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVK GDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAK SSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGL SSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIV TMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEM KKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSE KSEKKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKK RISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEK ERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERL RRAMELRRRREIAERERRERERIRIIREREERERLQRER ERLEIERQKLERERMERERLERERIRIEQERRKEAERIA REREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWS ENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPE SSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYP KNFSDSRRNEPPPPRNELRESDRREVRGERDERRTVIIH DRPDITHPRHPREAGPNPSRPTSWKSEGSMSTDKRETRV ERPERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVI TDRGGGSQHYPEERHVVERHGRDTSGPRKEWHGPPSQGP SYHDTRRMGDGRAGAGMITQHSSN |
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Database cross reference |
RefSeq Protein accession:NP_001013865
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Liver relevance
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HLPP validation |
Yes/No |
Yes |
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Project name |
Human Liver Organelles; |
Ontology annotation
| GO-C |
GO:0005634;C:nucleus;IEA:UniProtKB-SubCell. |
|
GO-F |
GO:0000166;F:nucleotide binding;IEA:InterPro. GO:0003723;F:RNA binding;IEA:UniProtKB-KW. |
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GO-P |
GO:0006915;P:apoptosis;IEA:UniProtKB-KW. GO:0006355;P:regulation of transcription, DNA-dependent;IEA:UniProtKB-KW. GO:0006351;P:transcription, DNA-dependent;IEA:UniProtKB-KW. |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
|
HuLPr45751 |
PHOSPHORYLATION |
800 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr45751 |
ACETYLATION |
1024 |
K |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
515 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
343 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
144 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
436 |
T |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
583 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
909 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr45751 |
ACETYLATION |
401 |
K |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr45751 |
ACETYLATION |
406 |
K |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
1019 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
1021 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
477 |
S |
PhosphoSitePlus |
LTP HTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
482 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
170 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
1002 |
S |
PhosphoSitePlus |
LTP HTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
1014 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
550 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
74 |
T |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
14 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
748 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
93 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
97 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
421 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
543 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
551 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
553 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
289 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
590 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
995 |
T |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr45751 |
PHOSPHORYLATION |
344 |
S |
PhosphoSitePlus |
HTP |
N |
|
