Home - LiverAtlas

Choose one of the five choices you want to search:

Gene, Transcriptome, Protein, Pathway or Disease.

LiverAtlas Protein ID	HuLPr45772
Uniprot ID	SMAP2_HUMAN
Uniprot Acc	Q8WU79;B2R7T1;B7Z8V2;D3DPV2;Q5QPL2;Q96C93;Q9NST2;Q9UJL8;
Protein name	Stromal membrane-associated protein 2
Comment	FUNCTION:GTPase activating protein that acts on ARF1. Can also activate ARF6 (in vitro). May play a role in clathrin-dependent retrograde transport from early endosomes to the trans-Golgi network (By similarity).\|\|SUBUNIT:Interacts with ARF1. Interacts with PICALM and clathrin heavy chains (By similarity).\|\|SUBCELLULAR LOCATION:Cytoplasm. Note=Detected in multiple foci throughout the cytoplasm and in juxtanuclear structures (By similarity).\|\|ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8WU79-1; Sequence=Displayed; Name=2; IsoId=Q8WU79-2; Sequence=VSP 018504;\|\|SIMILARITY:Contains 1 Arf-GAP domain.
Subcellular localization	Cytoplasm.
Gene name	small ArfGAP2
Protein sequence	MTGKSVKDVDRYQAVLANLLLEEDNKFCADCQSKGPRWAS WNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQ CMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIRDKY EKKKYMDRSLDINAFRKEKDDKWKRGSEPVPEKKLEPVV FEKVKMPQKKEDPQLPRKSSPKSTAPVMDLLGLDAPVAC SIANSKTSNTLEKDLDLLASVPSPSSSGSRKVVGSMPTA GSAGSVPENLNLFPEPGSKSEEIGKKQLSKDSILSLYGS QTPQMPTQAMFMAPAQMAYPTAYPSFPGVTPPNSIMGSM MPPPVGMVAQPGASGMVAPMAMPAGYMGGMQASMMGVPN GMMTTQQAGYMAGMAAMPQTVYGVQPAQQLQWNLTQMTQ QMAGMNFYGANGMMNYGQSMSGGNGQAANQTLSPQMWK
Database cross reference	RefSeq Protein accession:NP_001185907 RefSeq Protein gi:312176431

GO-C	GO:0005737;C:cytoplasm;IDA:HPA. GO:0005634;C:nucleus;IDA:HPA.
GO-F	GO:0008060;F:ARF GTPase activator activity;IEA:InterPro. GO:0008270;F:zinc ion binding;IEA:InterPro.
GO-P	GO:0032312;P:regulation of ARF GTPase activity;IEA:InterPro.