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Protein basic information

LiverAtlas Protein ID

HuLPr45979

Uniprot ID

SP5_HUMAN

Uniprot Acc

Q6BEB4;

Protein name

Transcription factor Sp5

Comment

FUNCTION:Binds to GC boxes promoters elements. Probable transcriptional activator that has a role in the coordination of changes in transcription required to generate pattern in the developing embryo (By similarity).||SUBCELLULAR LOCATION:Nucleus (By similarity).||SIMILARITY:Belongs to the Sp1 C2H2-type zinc-finger protein family.||SIMILARITY:Contains 3 C2H2-type zinc fingers.

Subcellular localization

Nucleus(By similarity).

Gene name

Sp5 transcription factor

Protein sequence

MAAVAVLRNDSLQAFLQDRTPSASPDLGKHSPLALLAATC SRIGQPGAAAPPDFLQVPYDPALGSPSRLFHPWTADMPA HSPGALPPPHPSLGLTPQKTHLQPSFGAAHELPLTPPAD PSYPYEFSPVKMLPSSMAALPASCAPAYVPYAAQAALPP GYSNLLPPPPPPPPPPTCRQLSPNPAPDDLPWWSIPQAG AGPGASGVPGSGLSGACAGAPHAPRFPASAAAAAAAAAA LQRGLVLGPSDFAQYQSQIAALLQTKAPLAATARRCRRC RCPNCQAAGGAPEAEPGKKKQHVCHVPGCGKVYGKTSHL KAHLRWHTGERPFVCNWLFCGKSFTRSDELQRHLRTHTG EKRFACPECGKRFMRSDHLAKHVKTHQNKKLKVAEAGVKREDARDL

Database cross reference

RefSeq Protein accession:NP_001003845
RefSeq Protein gi:51468067

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;French Liver;

Ontology annotation

GO-C

GO:0005634;C:nucleus;IEA:UniProtKB-SubCell.

GO-F

GO:0003677;F:DNA binding;IEA:UniProtKB-KW. GO:0008270;F:zinc ion binding;IEA:InterPro.

GO-P

GO:0006355;P:regulation of transcription, DNA-dependent;IEA:UniProtKB-KW. GO:0006351;P:transcription, DNA-dependent;IEA:UniProtKB-KW.

Post-translational modification

LiverAtlas Protein ID

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr45979

PHOSPHORYLATION

340

S

PhosphoSitePlus

18162225

LTP

N