Protein basic information
| LiverAtlas Protein ID |
HuLPr45989 |
|
Uniprot ID |
|
|
Uniprot Acc |
Q07617;A6NP70;Q7Z5G1; |
|
Protein name |
Sperm-associated antigen 1 |
|
Comment |
FUNCTION:Plays a role in fertilization. Binds GTP and has GTPase activity.||SUBCELLULAR LOCATION:Cytoplasm.||TISSUE SPECIFICITY:Detected in sperm and testis, in particular in pachytene primary spermatocytes.||MISCELLANEOUS:Antibodies against SPAG1 interfere with fertilization (By similarity).||SIMILARITY:Contains 9 TPR repeats.||SEQUENCE CAUTION:Sequence=AAH55091.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence; |
|
Subcellular localization |
Cytoplasm. |
|
Gene name |
|
|
Protein sequence
|
MTTKDYPSLWGFGTTKTFKIPIEHLDFKYIEKCSDVKHLE KILCVLRSGEEGYYPELTEFCEKHLQALAPESRALRKDK PAATAASFTAEEWEKIDGDIKSWVSEIKKEEDKMHFHET ETFPAMKDNLPPVRGSNSCLHVGKEKYSKRPTKKKTPRD YAEWDKFDVEKECLKIDEDYKEKTVIDKSHLSKIETRID TAGLTEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRS ISALPTVVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPG NVKALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAK KTLSEVERDLKNSEAASETQTKGKRMVIQEIENSEDEEG KSGRKHEDGGGDKKPAEPAGAARAAQPCVMGNIQKKLTG KAEGGKRPARGAPQRGQTPEAGADKRSPRRASAAAAAGG GATGHPGGGQGAENPAGLKSQGNELFRSGQFAEAAGKYS AAIALLEPAGSEIADDLSILYSNRAACYLKEGNCSGCIQ DCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKTV LQIDCGLQLANDSVNRLSRILMELDGPNWREKLSPIPAV PASVPLQAWHPAKEMISKQAGDSSSHRQQGITDEKTFKA LKEEGNQCVNDKNYKDALSKYSECLKINNKECAIYTNRA LCYLKLCQFEEAKQDCDQALQLADGNVKAFYRRALAHKG LKNYQKSLIDLNKVILLDPSIIEAKMELEEVTRLLNLKD KTAPFNKEKERRKIEIQEVNEGKEEPGRPAGEVSMGCLA SEKGGKSSRSPEDPEKLPIAKPNNAYEFGQIINALSTRK DKEACAHLLAITAPKDLPMFLSNKLEGDTFLLLIQSLKN NLIEKDPSLVYQHLLYLSKAERFKMMLTLISKGQKELIE QLFEDLSDTPNNHFTLEDIQALKRQYEL |
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Database cross reference |
RefSeq Protein accession:NP_003105
|
Liver relevance
|
HLPP validation |
Yes/No |
Yes |
|
Project name |
Chinese Liver;Human Liver Organelles; |
Ontology annotation
| GO-C |
GO:0005737;C:cytoplasm;IEA:UniProtKB-SubCell. |
|
GO-F |
GO:0005525;F:GTP binding;IEA:UniProtKB-KW. GO:0016787;F:hydrolase activity;IEA:UniProtKB-KW. |
|
GO-P |
GO:0007338;P:single fertilization;TAS:ProtInc. |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
|
HuLPr45989 |
PHOSPHORYLATION |
347 |
S |
Phospho-ELM |
HTP |
N |
 
|
|
|
HuLPr45989 |
PHOSPHORYLATION |
791 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr45989 |
PHOSPHORYLATION |
177 |
Y |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr45989 |
PHOSPHORYLATION |
639 |
Y |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr45989 |
PHOSPHORYLATION |
646 |
Y |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr45989 |
PHOSPHORYLATION |
347 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr45989 |
PHOSPHORYLATION |
791 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr45989 |
PHOSPHORYLATION |
225 |
Y |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr45989 |
PHOSPHORYLATION |
660 |
Y |
PhosphoSitePlus |
LTP HTP |
N |
|
|
|
HuLPr45989 |
PHOSPHORYLATION |
354 |
S |
PhosphoSitePlus |
HTP |
N |
|
