Protein basic information
| LiverAtlas Protein ID |
HuLPr46211 |
|
Uniprot ID |
|
|
Uniprot Acc |
Q9BWW4;A8K0A9;Q5T860;Q5T861;Q9BTM0;Q9BWW3; |
|
Protein name |
Single-stranded DNA-binding protein 3 |
|
Comment |
FUNCTION:May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region (By similarity).||SUBCELLULAR LOCATION:Nucleus (By similarity).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q9BWW4-1; Sequence=Displayed; Name=2; IsoId=Q9BWW4-2; Sequence=VSP 006260; Name=3; IsoId=Q9BWW4-3; Sequence=VSP 006261;||TISSUE SPECIFICITY:Highly expressed in all hematopoietic tissues, including spleen, lymph node, peripheral blood, bone marrow, thymus, and fetal liver, with highest expression in thymus and fetal liver. Expression is also high in heart, brain, kidney, and skeletal muscle.||SIMILARITY:Contains 1 LisH domain. |
|
Subcellular localization |
Nucleus(By similarity). |
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Gene name |
|
|
Protein sequence
|
MFAKGKGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTF LSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRDT CEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPP GFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYA GGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNM GGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMP GINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGG PPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNIS GISNPPGTPRDDGELGGNFLHSFQNDNYSPSMTMSV |
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Database cross reference |
RefSeq Protein accession:NP_001009955
|
Ontology annotation
| GO-C |
GO:0005634;C:nucleus;IEA:UniProtKB-SubCell. |
|
GO-F |
GO:0003697;F:single-stranded DNA binding;IEA:InterPro. GO:0030528;F:transcription regulator activity;IEA:InterPro. |
|
GO-P |
GO:0006355;P:regulation of transcription, DNA-dependent;IEA:UniProtKB-KW. GO:0006351;P:transcription, DNA-dependent;IEA:UniProtKB-KW. |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
|
HuLPr46211 |
PHOSPHORYLATION |
347 |
S |
Phospho-ELM |
HTP |
N |
 
|
|
|
HuLPr46211 |
PHOSPHORYLATION |
360 |
T |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr46211 |
PHOSPHORYLATION |
381 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr46211 |
PHOSPHORYLATION |
387 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr46211 |
PHOSPHORYLATION |
381 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr46211 |
PHOSPHORYLATION |
387 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr46211 |
PHOSPHORYLATION |
352 |
S |
PhosphoSitePlus |
LTP HTP |
N |
|
|
|
HuLPr46211 |
PHOSPHORYLATION |
385 |
T |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr46211 |
PHOSPHORYLATION |
23 |
Y |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr46211 |
PHOSPHORYLATION |
25 |
Y |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr46211 |
PHOSPHORYLATION |
156 |
Y |
PhosphoSitePlus |
LTP HTP |
N |
|
|
|
HuLPr46211 |
PHOSPHORYLATION |
347 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr46211 |
PHOSPHORYLATION |
360 |
T |
PhosphoSitePlus |
LTP |
N |
|
