Protein basic information
| LiverAtlas Protein ID |
HuLPr46652 |
|
Uniprot ID |
|
|
Uniprot Acc |
Q9HBM6;B2RUZ9;Q9Y2S3; |
|
Protein name |
Transcription initiation factor TFIID subunit 9B |
|
Comment |
FUNCTION:Essential for cell viability. TAF9 and TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. May have a role in gene regulation associated with apoptosis. TAFs are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription.||SUBUNIT:Binds TAF5 and TAF6. Component of TFIID and the TATA- binding protein-free TAF complex (TFTC). TFIID is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). Binds N-terminal domain of p53/TP53 which is essential for transcription.||SUBCELLULAR LOCATION:Nucleus (By similarity).||SIMILARITY:Belongs to the TAF9 family. |
|
Subcellular localization |
Nucleus(By similarity). |
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Gene name |
TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
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Protein sequence
|
MESGKMAPPKNAPRDALVMAQILKDMGITEYEPRVINQML EFAFRYVTTILDDAKIYSSHAKKPNVDADDVRLAIQCRA DQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPD RYCLTAPNYRLKSLIKKGPNQGRLVPRLSVGAVSSKPTT PTIATPQTVSVPNKVATPMSVTSQRFTVQIPPSQSTPVK PVPATTAVQNVLINPSMIGPKNILITTNMVSSQNTANEA NPLKRKHEDDDDNDIM |
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Database cross reference |
RefSeq Protein accession:NP_057059
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Ontology annotation
| GO-C |
GO:0005669;C:transcription factor TFIID complex;IDA:UniProtKB. GO:0033276;C:transcription factor TFTC complex;IDA:UniProtKB. |
|
GO-F |
GO:0003677;F:DNA binding;IEA:InterPro. GO:0005515;F:protein binding;IPI:UniProtKB. GO:0003714;F:transcription corepressor activity;IC:BHF-UCL. |
|
GO-P |
GO:0043066;P:negative regulation of apoptosis;IMP:BHF-UCL. GO:0010553;P:negative regulation of gene-specific transcription from RNA polymerase II promoter;IMP:BHF-UCL. GO:0030307;P:positive regulation of cell growth;IMP:UniProtKB. GO:0006352;P:transcrip |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
|
HuLPr46652 |
PHOSPHORYLATION |
159 |
T |
PhosphoSitePlus |
LTP |
N |
 
|
|
|
HuLPr46652 |
PHOSPHORYLATION |
177 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr46652 |
PHOSPHORYLATION |
174 |
T |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr46652 |
PHOSPHORYLATION |
153 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr46652 |
PHOSPHORYLATION |
157 |
T |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr46652 |
PHOSPHORYLATION |
156 |
T |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr46652 |
PHOSPHORYLATION |
152 |
S |
PhosphoSitePlus |
HTP |
N |
|
