Choose one of the five choices you want to search:

Gene, Transcriptome, Protein, Pathway or Disease. 

Protein basic information

LiverAtlas Protein ID

HuLPr46997

Uniprot ID

THMS2_HUMAN

Uniprot Acc

Q5TEJ8;A2RTZ3;B4DZT9;B4DZY3;O60560;Q5TEJ1;Q5TEJ9;Q5TEK1;Q68DP4;Q9BYB6;Q9NS90;

Protein name

Protein THEMIS2

Comment

FUNCTION:May constitute a control point in macrophage inflammatory response, promoting LPS-induced TNF production.||SUBUNIT:When phosphorylated, interacts with LYN. Interacts with VAV1 and GRB2 (By similarity).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=6; Name=1; IsoId=Q5TEJ8-1; Sequence=Displayed; Name=2; Synonyms=ICB1-beta; IsoId=Q5TEJ8-2; Sequence=VSP 015326, VSP 015327; Note=No experimental confirmation available; Name=3; Synonyms=ICB1-gamma; IsoId=Q5TEJ8-3; Sequence=VSP 015330; Name=4; IsoId=Q5TEJ8-4; Sequence=VSP 015328, VSP 015329; Name=5; IsoId=Q5TEJ8-5; Sequence=VSP 037967; Note=No experimental confirmation available; Name=6; IsoId=Q5TEJ8-6; Sequence=VSP 037966; Note=No experimental confirmation available;||TISSUE SPECIFICITY:Expressed in different endometrial adenocarcinoma cell lines and various other cell lines aprat from the prostate cell line LNCAP and the ovarian cancer cell line BG- 1.||INDUCTION:By contact to a reconstituted bas

Gene name

chromosome 1 open reading frame 38

Protein sequence

MEPVPLQDFVRALDPASLPRVLRVCSGVYFEGSIYEISGN ECCLSTGDLIKVTQVRLQKVVCENPKTSQTMELAPNFQG YFTPLNTPQSYETLEELVSATTQSSKQLPTCFMSTHRIV TEGRVVTEDQLLMLEAVVMHLGIRSARCVLGMEGQQVIL HLPLSQKGPFWTWEPSAPRTLLQVLQDPALKDLVLTCPT LPWHSLILRPQYEIQAIMHMRRTIVKIPSTLEVDVEDVT ASSRHVHFIKPLLLSEVLAWEGPFPLSMEILEVPEGRPI FLSPWVGSLQKGQRLCVYGLASPPWRVLASSKGRKVPRH FLVSGGYQGKLRRRPREFPTAYDLLGAFQPGRPLRVVAT KDCEGEREENPEFTSLAVGDRLEVLGPGQAHGAQGSDVD VLVCQRLSDQAGEDEEEECKEEAESPERVLLPFHFPGSF VEEMSDSRRYSLADLTAQFSLPCEVKVVAKDTSHPTDPL TSFLGLRLEEKITEPFLVVSLDSEPGMCFEIPPRWLDLT VVKAKGQPDLPEGSLPIATVEELTDTFYYRLRKLPACEI QAPPPRPPKNQGLSKQRRHSSEGGVKSSQVLGLQQHARL PKPKAKTLPEFIKDGSSTYSKIPAHRKGHRPAKPQRQDL DDDEHDYEEILEQFQKTI

Database cross reference

RefSeq Protein accession:NP_001034566
RefSeq Protein gi:87080817

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;Chinese Liver;

Ontology annotation

GO-P

GO:0007155;P:cell adhesion;TAS:ProtInc. GO:0006954;P:inflammatory response;IEA:UniProtKB-KW.

Pathway

Pathway name

IL2

Pathway name

TSH