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Protein basic information

LiverAtlas Protein ID

HuLPr47065

Uniprot ID

TIMD4_HUMAN

Uniprot Acc

Q96H15;

Protein name

T-cell immunoglobulin and mucin domain-containing protein 4

Comment

FUNCTION:Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Involved in regulating T-cell proliferation and lymphotoxin signaling. Ligand for HAVCR1/TIMD1 (By similarity).||SUBCELLULAR LOCATION:Membrane; Single-pass type I membrane protein (Potential).||DOMAIN:Recognizes phosphatidyl serine via its immunoglobulin domain.||SIMILARITY:Belongs to the immunoglobulin superfamily. TIM family.||SIMILARITY:Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Subcellular localization

Membrane;Single-pass type I membrane protein(Potential).

Gene name

T-cell immunoglobulin and mucin domain containing 4

Protein sequence

MSKEPLILWLMIEFWWLYLTPVTSETVVTEVLGHRVTLPC LYSSWSHNSNSMCWGKDQCPYSGCKEALIRTDGMRVTSR KSAKYRLQGTIPRGDVSLTILNPSESDSGVYCCRIEVPG WFNDVKINVRLNLQRASTTTHRTATTTTRRTTTTSPTTT RQMTTTPAALPTTVVTTPDLTTGTPLQMTTIAVFTTANT CLSLTPSTLPEEATGLLTPEPSKEGPILTAESETVLPSD SWSSVESTSADTVLLTSKESKVWDLPSTSHVSMWKTSDS VSSPQPGASDTAVPEQNKTTKTGQMDGIPMSMKNEMPIS QLLMIIAPSLGFVLFALFVAFLLRGKLMETYCSQKHTRL DYIGDSKNVLNDVQHGREDEDGLFTL

Database cross reference

RefSeq Protein accession:NP_001140198
RefSeq Protein gi:226498466

Ontology annotation

GO-C

GO:0016021;C:integral to membrane;IEA:UniProtKB-KW.