HuLPr47171

Uniprot ID

TM192_HUMAN

Uniprot Acc

Q8IY95;Q7Z3A1;Q8N928;

Protein name

Transmembrane protein 192

Comment

SUBUNIT:Homodimer (Probable).||SUBCELLULAR LOCATION:Lysosome membrane; Multi-pass membrane protein. Late endosome.||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8IY95-1; Sequence=Displayed; Name=2; IsoId=Q8IY95-2; Sequence=VSP 029502; Note=No experimental confirmation available;||TISSUE SPECIFICITY:Strongly expressed in kidney, liver, lung and pancreas.||PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.||PTM:Not N-glycosylated.||SIMILARITY:Belongs to the TMEM192 family.||SEQUENCE CAUTION:Sequence=CAD97974.1; Type=Erroneous initiation;

Subcellular localization

Lysosome membrane;Multi-pass membrane protein.Late endosome.

Gene name

transmembrane protein 192

Protein sequence

MAAGGRMEDGSLDITQSIEDDPLLDAQLLPHHSLQAHFRP RFHPLPTVIIVNLLWFIHLVFVVLAFLTGVLCSYPNPNE DKCPGNYTNPLKVQTVIILGKVILWILHLLLECYIQYHH SKIRNRGYNLIYRSTRHLKRLALMIQSSGNTVLLLILCM QHSFPEPGRLYLDLILAILALELICSLICLLIYTVKIRR FNKAKPEPDILEEEKIYAYPSNITSETGFRTISSLEEIV EKQGDTIEYLKRHNALLSKRLLALTSSDLGCQPSRT

Database cross reference

RefSeq Protein accession:NP_001093859
RefSeq Protein gi:154240704

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

GO:0005794;C:Golgi apparatus;IDA:HPA. GO:0016021;C:integral to membrane;IEA:UniProtKB-KW. GO:0005770;C:late endosome;IEA:UniProtKB-SubCell. GO:0005765;C:lysosomal membrane;IEA:UniProtKB-SubCell. GO:0005634;C:nucleus;IDA:HPA.

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr47171

PHOSPHORYLATION

15

T

PhosphoSitePlus

482000

HTP

N

HuLPr47171

PHOSPHORYLATION

213

Y

PhosphoSitePlus

451743

LTP

HTP

N

HuLPr47171

PHOSPHORYLATION

17

S

PhosphoSitePlus

481999

HTP

N