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Gene, Transcriptome, Protein, Pathway or Disease. 

Protein basic information

LiverAtlas Protein ID

HuLPr47482

Uniprot ID

TPPC4_HUMAN

Uniprot Acc

Q9Y296;A8K3A5;

Protein name

Trafficking protein particle complex subunit 4

Comment

FUNCTION:May play a role in vesicular transport from endoplasmic reticulum to Golgi.||SUBUNIT:Part of the multisubunit TRAPP (transport protein particle) complex. Interacts with TRAPPC2L. Interacts with SDC2 (By similarity).||INTERACTION:Q9CQA1:Trappc5 (xeno); NbExp=1; IntAct=EBI-722888, EBI-1172213;||SUBCELLULAR LOCATION:Golgi apparatus, cis-Golgi network (By similarity). Endoplasmic reticulum (By similarity).||SIMILARITY:Belongs to the TRAPP small subunits family. TRAPPC4 subfamily.

Subcellular localization

Golgi apparatus, cis-Golgi network(By similarity).Endoplasmic reticulum(By similarity).

Gene name

trafficking protein particle complex 4

Protein sequence

MAIFSVYVVNKAGGLIYQLDSYAPRAEAEKTFSYPLDLLL KLHDERVLVAFGQRDGIRVGHAVLAINGMDVNGRYTADG KEVLEYLGNPANYPVSIRFGRPRLTSNEKLMLASMFHSL FAIGSQLSPEQGSSGIEMLETDTFKLHCYQTLTGIKFVV LADPRQAGIDSLLRKIYEIYSDFALKNPFYSLEMPIRCE LFDQNLKLALEVAEKAGTFGPGS

Database cross reference

RefSeq Protein accession:NP_057230
RefSeq Protein gi:7706667

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0005801;C:cis-Golgi network;IEA:InterPro. GO:0030425;C:dendrite;ISS:UniProtKB. GO:0005783;C:endoplasmic reticulum;IEA:UniProtKB-SubCell. GO:0005795;C:Golgi stack;ISS:UniProtKB. GO:0008021;C:synaptic vesicle;ISS:UniProtKB.

GO-F

GO:0005515;F:protein binding;IPI:IntAct.

GO-P

GO:0016358;P:dendrite development;ISS:UniProtKB. GO:0006888;P:ER to Golgi vesicle-mediated transport;IEA:InterPro.

Post-translational modification

LiverAtlas Protein ID

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr47482

PHOSPHORYLATION

168

S

PhosphoSitePlus

18017079

LTP

N

Pathway

Pathway name

Syndecan-2-mediated_signaling_events